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A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
Published on: January 11, 2020
Comparison of Postoperative Cognitive Decline Using the Mini-Mental State Examination and Montreal Cognitive
Ismail Aytaç1, Betül Güven Aytaç1, Gokhan Demirelli2
1Anesthesiology, Ankara City Hospital, Ankara, TUR.
Abstract:
Introduction and aim Postoperative cognitive dysfunction (POCD) is an important complication associated with increased morbidity, mortality, and reduced quality of life. Generally, studies have focused on major surgery so there is little evidence of the incidence of cognitive dysfunction in minor surgery. We aimed to compare the Mini-Mental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA) in terms of detecting cognitive decline in elderly patients after elective inguinal herniorrhaphy procedure with general or spinal anesthesia. Material and methods This observational study was conducted from June 2014 to March 2015 at Ankara Numune Education and Research Hospital. The type of anesthesia was determined according to the anesthesiologist's preference who is blind to the study. Patients were grouped according to anesthesia received: general or spinal anesthesia. The MMSE and MoCA were evaluated presurgery and 24 hours after the operation. Results The postoperative (24th hour) MMSE scores of patients (26.23±2.77) were significantly lower than the preoperative scores (27.17±1.93) in only the general anesthesia group (p =0.003). The postoperative (24th hour) MoCA scores (22.87±3.88 for general and 23.13±4.08 for spinal anesthesia) were significantly lower than the preoperative scores (24.32±3.19 for general and 24.35±2.84 for spinal anesthesia) in both the general and spinal anesthesia groups (p =0.000 and 0.019, respectively). The incidence of postoperative cognitive dysfunction was 32.9% using the MoCA and 15.2% using the MMSE (p=0,018). Conclusion Early POCD is an important problem after elective minor surgeries, even with spinal anesthesia, in elderly patients. The MoCA is an alternative tool that can be more sensitive than the MMSE to identify cognitive decline in elderly patients undergoing minor surgeries under both general and spinal anesthesia.
Insights
Postoperative cognitive dysfunction (POCD) is common in elderly patients after minor surgery. The Montreal Cognitive Assessment (MoCA) is more sensitive than the Mini-Mental State Examination (MMSE) for detecting this decline.
Area of Science:
- Anesthesiology
- Geriatric Medicine
- Neuroscience
Background:
- Postoperative cognitive dysfunction (POCD) is a significant complication impacting patient outcomes after surgery.
- While studied in major surgeries, less is known about POCD incidence following minor procedures in the elderly.
- Existing cognitive assessment tools may vary in their sensitivity to detect early cognitive changes.
Purpose of the Study:
- To compare the efficacy of the Mini-Mental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA) in identifying cognitive decline in elderly patients undergoing elective inguinal herniorrhaphy.
- To assess the incidence of POCD after minor surgery under general versus spinal anesthesia.
Main Methods:
- An observational study involving elderly patients undergoing elective inguinal herniorrhaphy.
- Patients were grouped to receive either general or spinal anesthesia.
- Cognitive function was assessed using MMSE and MoCA pre-surgery and 24 hours post-operation.
Main Results:
- The Montreal Cognitive Assessment (MoCA) detected significant cognitive decline in both general and spinal anesthesia groups (p < 0.05).
- The Mini-Mental State Examination (MMSE) only showed significant decline in the general anesthesia group (p = 0.003).
- POCD incidence was higher with MoCA (32.9%) compared to MMSE (15.2%) (p=0.018).
Conclusions:
- Early POCD is a relevant issue in elderly patients even after minor elective surgeries, including those under spinal anesthesia.
- The MoCA demonstrates greater sensitivity than the MMSE in detecting cognitive decline in this patient population.
- MoCA is a valuable tool for identifying elderly patients at risk of POCD after minor surgical procedures.

