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Published on: February 20, 2017
Determinants of minute ventilation-carbon dioxide production relationship in Chagas cardiomyopathy
Lucas Frois Fernandes Oliveira1, Janaina Martins Andrade2,3, Pedro Henrique Scheidt Figueiredo1,2
1Universidade Federal dos Vales do Jequitinhonha e Mucuri, Departamento de Fisioterapia, Diamantina, MG, Brasil.
Introduction:
The minute ventilation-carbon dioxide production relationship (VE/VCO2 slope) is among the main prognostic factors of Chagas cardiomyopathy whose determinants remain unknown.
Methods:
Seventy-eight patients with Chagas cardiomyopathy were evaluated using clinical assessment, cardiopulmonary exercise test, echocardiography, and International Physical Activity Questionnaire.
Results:
Age, functional class, International Physical Activity Questionnaire score, and dilated cardiomyopathy with systolic dysfunction were independent determinants of VE/VCO2 slope, and these variables explained 63% of its variance.
Conclusions:
The VE/VCO2 slope was related to age, functional class, physical activity level, and dilated cardiomyopathy with systolic dysfunction in patients with Chagas cardiomyopathy.
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