Related Experiment Video
Updated: Oct 13, 2025

11:18
Generation of Comprehensive Thoracic Oncology Database - Tool for Translational Research
Published on: January 22, 2011
16.2K
Implementing multidisciplinary tumor boards in oncology: a narrative review
Max S Mano1,2, Fadil T Çitaku2, Paul Barach2,3,4
1Grupo Oncoclínicas, São Paulo, Brazil.
Future Oncology (London, England)
|November 17, 2021
Summary
Multidisciplinary tumor boards (MTBs) offer a structured approach to improve cancer care by leveraging teamwork and robust systems, similar to high-safety industries. This review examines MTB effectiveness and implementation challenges in oncology.
Area of Science:
- Oncology
- Healthcare Management
- Systems Engineering
Background:
- Healthcare complexity necessitates robust systems, unlike aviation or nuclear power.
- Multidisciplinary tumor boards (MTBs) represent an evidence-based strategy for enhancing oncology practice.
- Current research indicates promising correlations between MTBs and improved cancer outcomes.
Purpose of the Study:
- To define and characterize multidisciplinary tumor boards (MTBs) in contemporary oncology.
- To review existing literature on the effectiveness of MTBs in cancer care.
- To identify and discuss challenges associated with MTB implementation and sustainability.
Main Methods:
- Commentary-type narrative review.
- Synthesis of expert opinion.
- Literature review with supportive citations.
Main Results:
- MTBs are an organizational approach to improve oncology practice.
- Evidence suggests positive correlations between MTBs and cancer outcomes.
- Implementation and maintenance of MTBs present specific challenges.
Conclusions:
- MTBs are a valuable, evidence-based model for enhancing cancer care delivery.
- Addressing implementation challenges is crucial for maximizing MTB benefits.
- Further research and strategic planning can optimize MTB integration into oncology practice.
Related Concept Videos
Cancer Therapies
8.1K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
8.1K
Cancer Survival Analysis
478
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
478
Tumor Immunotherapy
726
Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
726
Treatment Resistant Cancers
3.4K
Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
3.4K
Targeted Cancer Therapies
7.9K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
There are several types of targeted therapies against...
7.9K
Combination Therapies and Personalized Medicine
5.2K
Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
5.2K

