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Related Experiment Video

Updated: Oct 13, 2025

Novel Sequence Discovery by Subtractive Genomics
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ProSeqViewer: an interactive, responsive and efficient TypeScript library for visualization of sequences and

Martina Bevilacqua1, Lisanna Paladin2, Silvio C E Tosatto1

  • 1Department of Biomedical Sciences, University of Padua, 35121 Padova, Italy.

Bioinformatics (Oxford, England)
|November 17, 2021
PubMed
Summary
This summary is machine-generated.

ProSeqViewer is a new tool for visualizing biological sequence data and annotations. This lightweight, interactive library enhances biological data analysis and integration into web resources.

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Area of Science:

  • Bioinformatics
  • Computational Biology
  • Genomics

Background:

  • Biological data, including nucleotide and amino acid sequences, is rapidly growing in volume and complexity.
  • Mapping biological data to sequences is crucial for analysis, classification, and prediction.
  • Sequence comparison facilitates knowledge transfer, functional domain mapping, and identification of binding/modification sites.

Purpose of the Study:

  • To develop a tool for visualizing annotations on single sequences and multiple sequence alignments.
  • To create a modular, integrable component for web-based biological data resources.

Main Methods:

  • Developed ProSeqViewer as a lightweight, fast, and interactive TypeScript library.
  • Ensured ProSeqViewer generates pure HTML for broad browser and operating system compatibility.
  • Designed ProSeqViewer as a modular component for integration into static or dynamic web resources.

Main Results:

  • ProSeqViewer provides intuitive visualization of sequence features.
  • The tool is lightweight, fast, interactive, dynamic, and responsive across all screen sizes.
  • ProSeqViewer generates pure HTML, ensuring cross-browser and cross-platform compatibility.
  • The library supports event exchange with other visualization components and is already in use by biological databases.

Conclusions:

  • ProSeqViewer is a versatile, open-source tool for enhancing biological sequence data visualization.
  • Its modular design and web compatibility facilitate integration into diverse biological databases and resources.
  • The library supports advanced sequence analysis tasks through intuitive annotation visualization.