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Updated: Oct 13, 2025

Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses
Published on: November 10, 2023
The Pandemic of Coronavirus Disease 2019 (COVID-19)
1Department of Molecular Medicine, Faculty of Medicine, University of Malaya, 50603, Kuala Lumpur, Malaysia.
Insights
The novel coronavirus (SARS-CoV-2) causes COVID-19, a pandemic illness. This review covers SARS-CoV-2 transmission, infectiousness, symptoms, and current treatments for COVID-19.
Area of Science:
- Virology
- Epidemiology
- Public Health
Background:
- The emergence of SARS-CoV-2, the virus responsible for COVID-19, has led to a global pandemic.
- COVID-19 presents with pneumonia and potential complications like respiratory distress syndrome and death.
- SARS-CoV-2 shares genetic similarities with SARS and disease features with influenza.
Purpose of the Study:
- To provide an update on the COVID-19 pandemic.
- To review the symptoms and transmission routes of SARS-CoV-2.
- To discuss the high infectivity, available treatments, and comorbidities associated with COVID-19.
Main Methods:
- Literature review of scientific publications and WHO reports.
- Analysis of genetic similarities between SARS-CoV-2, SARS, and influenza viruses.
- Compilation of current data on COVID-19 symptoms, transmission, and treatments.
Main Results:
- SARS-CoV-2 is a zoonotic virus that has adapted to human transmission, declared a pandemic by WHO.
- The virus exhibits high infectiousness, necessitating global research into vaccines and antivirals.
- Understanding transmission, symptoms, and comorbidities is crucial for managing the pandemic.
Conclusions:
- COVID-19 is a significant global health threat requiring ongoing research and public health measures.
- Further studies are needed to develop effective vaccines and antiviral treatments.
- Comprehensive knowledge of SARS-CoV-2 is essential for pandemic control and patient management.
Abstract:
Currently, the world is facing the emergence of a virus that causes pneumonia in humans, which has a higher probability of causing complications, including respiratory distress syndrome and death. The new coronavirus 2019 (2019-nCoV), which is currently known as SARS-CoV-2, is the cause of the Coronavirus disease 2019 (COVID-19). This virus was first detected in Wuhan, Hubei Province of China, and appears to have been a zoonotic infection that has now adapted to humans. On March 11, 2020, COVID-19 was announced as a pandemic by the World Health Organisation (WHO), causing widespread panic worldwide. SARS-CoV-2 is genetically similar to the 2003 Severe Acute Respiratory Syndrome-related (SARS) and shares many similarities with the disease features of influenza virus infection. Scientists around the world are racing towards the development of vaccines and antivirals for COVID-19. This review will provide an update of COVID-19, a brief review of the symptoms and route of transmission of the SARS-CoV-2 virus, the reason why it is highly infectious, as well as the currently available treatments and comorbidities.
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