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Published on: April 22, 2019
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Primary Cutaneous Atypical Spindle Cell Lipomatous Tumor
Madeline S Tchack1, Michael Broscius2, Martin Reichel3
1Memorial Sloan Kettering Cancer Center, New York, NY 10065-6007, USA.
Case Reports in Pathology
|November 18, 2021
Summary
A rare skin tumor, atypical spindle cell/pleomorphic lipomatous tumor (ASPLT), was documented. This ASPLT case showed no recurrence or metastasis five years post-surgery.
Area of Science:
- Dermatopathology
- Surgical Pathology
- Oncology
Background:
- Atypical spindle cell/pleomorphic lipomatous tumor (ASPLT) is a rare mesenchymal neoplasm.
- Cutaneous ASPLT is exceptionally uncommon, with limited documented cases.
Observation:
- This report details an exophytic, pedunculated nodule in a 74-year-old male patient.
- Histopathological examination confirmed the lesion as an ASPLT.
Findings:
- The ASPLT was exclusively confined to the papillary and reticular dermis.
- This represents the fourth documented instance of cutaneous ASPLT.
- Despite significant pleomorphic histological features, the tumor showed no metastasis or recurrence at five-year follow-up.
Implications:
- This case expands the understanding of ASPLT presentation and behavior in the skin.
- It highlights the potential for favorable outcomes even with histologically atypical features.
- Further research into ASPLT pathogenesis and management is warranted.

