Related Experiment Video
Updated: Oct 13, 2025
10:41
Leveraging CyVerse Resources for De Novo Comparative Transcriptomics of Underserved Non-model Organisms
Published on: May 9, 2017
9.4K
Ensembl Genomes 2022: an expanding genome resource for non-vertebrates
Andrew D Yates1, James Allen1, Ridwan M Amode1
1European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SD, UK.
Nucleic Acids Research
|November 18, 2021
Summary
Ensembl Genomes now offers the largest collection of plant, fungal, and metazoan genomes, enhancing genomic resources. This expansion includes improved gene annotation and pangenome analysis for broader research applications.
Area of Science:
- Genomics
- Bioinformatics
- Comparative Genomics
Background:
- Ensembl Genomes complements Ensembl by providing non-vertebrate genomic data.
- The combined resources offer a unified interface for diverse genomic information.
- Existing resources cover genome sequence, annotation, variation, and transcriptomics.
Purpose of the Study:
- To announce a significant expansion of Ensembl Genomes' non-vertebrate genomic data.
- To detail new features including improved gene annotation and pangenome analysis.
- To outline future developments and integration with Ensembl.
Main Methods:
- Integration of new plant, metazoan, and fungal genome assemblies.
- Development of enhanced gene annotation pipelines.
- Implementation of bacterial genome redundancy reduction strategies.
- Introduction of AlphaFold structure visualization.
Main Results:
- The largest ever increase in plant, metazoan, and fungal genomes.
- Creation of one of the world's most comprehensive genomic databases.
- Reduced redundancy in the Bacteria portal.
- New capabilities for pangenome analysis and rapid data dissemination.
Conclusions:
- Ensembl Genomes has significantly expanded its non-vertebrate genomic data.
- New analytical tools and visualizations enhance data accessibility and utility.
- Future plans focus on deeper integration with Ensembl and enhanced microbial support.
Related Concept Videos
03:21Genome Size and the Evolution of New Genes
2.7K
2.7K
02:54Evolutionary Relationships through Genome Comparisons
6.4K
Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
6.4K
02:51Multi-species Conserved Sequences
4.3K
Next-generation sequencing technologies have created large genomic databases of a variety of animals and plants. Ever since the human genome project was completed, scientists studied the genome of primates, mammals, and other phylogenetically distant living beings. Such large-scale studies have provided new insights into the evolutionary relationship between organisms.
Although the genome of each species varies greatly from each other, a few sequences are highly conserved. Such conserved...
Although the genome of each species varies greatly from each other, a few sequences are highly conserved. Such conserved...
4.3K
02:02Genomics
37.9K
Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
37.9K
03:36Genome Annotation and Assembly
19.5K
The genome refers to all of the genetic material in an organism. It can range from a few million base pairs in microbial cells to several billion base pairs in many eukaryotic organisms. Genome assembly refers to the process of taking the DNA sequencing data and putting it all back together in a correct order to create a close representation of the original genome. This is followed by the identification of functional elements on the newly assembled genome, a process called genome annotation.
19.5K
00:58Genomic DNA in Eukaryotes
49.2K
Eukaryotes have large genomes compared to prokaryotes. To fit their genomes into a cell, eukaryotic DNA is packaged extraordinarily tightly inside the nucleus. To achieve this, DNA is tightly wound around proteins called histones, which are packaged into nucleosomes that are joined by linker DNA and coil into chromatin fibers. Additional fibrous proteins further compact the chromatin, which is recognizable as chromosomes during certain phases of cell division.
49.2K