Sunitinib induced colitis manifesting as invasive diarrhea in a patient with renal cell carcinoma

Yasemin Gündoğdu1, Orhan Cem Deniz1, Didem Saka2

  • 1Department of Internal Medicine, School of Medicine, Acıbadem Mehmet Ali Aydınlar University, Turkey.

Abstract

Insights

Sunitinib treatment for renal cell carcinoma can cause drug-induced colitis. This case highlights the importance of monitoring for diarrhea and managing sunitinib-associated colitis, even with unusual pathological findings.

Area of Science:

  • Oncology
  • Gastroenterology

Background:

  • Sunitinib, a tyrosine kinase inhibitor, treats renal cell carcinoma, gastrointestinal stromal tumors, and pancreatic neuroendocrine tumors.
  • Diarrhea is a common side effect of tyrosine kinase inhibitors.

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