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Related Concept Videos

Bacterial Phylum Spirochaetes01:30

Bacterial Phylum Spirochaetes

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Spirochetes, unique bacteria in the phylum Spirochaetes, are gram-negative, motile, tightly coiled, slender, and flexible. They inhabit aquatic sediments and animals, with some causing diseases like syphilis. Spirochetes are classified into eight genera based on habitat, pathogenicity, phylogeny, and characteristics.Their distinctive motility arises from endoflagella, located within the cell’s periplasm. These endoflagella anchor at the cell poles and extend along the cell length, encased...
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Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...
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Bacterial Phylum Tenericutes01:24

Bacterial Phylum Tenericutes

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The phylum Tenericutes, which includes the single class Mollicutes, comprises bacteria that lack cell walls. The term "Mollicutes" derives from the Latin word mollis, meaning "soft." These organisms are among the smallest known and are commonly referred to as mycoplasmas due to the prominence of the genus Mycoplasma, which includes well-known human pathogens. Despite their inability to stain gram-positively (a result of their lack of cell walls), mycoplasmas are phylogenetically related to the...
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Intestinal Spirochaetosis-A case series from the developing world.

Zain Majid1, Ghazi Abrar2, Hina Ismail2

  • 1Consultant, Department of Hepato-gastroenterology66810, Sindh Institute of Urology and Transplantation, SIUT, Karachi, Pakistan.

Tropical Doctor
|November 18, 2021
PubMed
Summary

Intestinal spirochetosis, a rare bacterial condition, presents with gastrointestinal issues. A short metronidazole course effectively treated four diverse cases, offering a potential therapeutic option.

Keywords:
Intestinal spirochetosislower socio-economic statusmetronidazole

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Area of Science:

  • Microbiology
  • Gastroenterology

Background:

  • Spirochaetes are diverse Gram-negative bacteria.
  • Some spirochaetes cause significant human diseases like Lyme disease and syphilis.
  • Intestinal spirochetosis is a rare condition with non-specific gastrointestinal symptoms.

Purpose of the Study:

  • To describe four cases of intestinal spirochetosis.
  • To highlight the diagnostic approach and successful treatment of this rare condition.

Main Methods:

  • Case series describing four patients with intestinal spirochetosis.
  • Diagnosis confirmed via endoscopy with biopsy.
  • Treatment administered using a short course of metronidazole.

Main Results:

  • Four patients with varying demographics presented with chronic gastrointestinal symptoms.
  • Endoscopy and biopsy confirmed intestinal spirochetosis in all cases.
  • All patients showed successful treatment outcomes with metronidazole.

Conclusions:

  • Intestinal spirochetosis, though rare, should be considered in patients with persistent gastrointestinal complaints.
  • Endoscopy with biopsy is crucial for diagnosis.
  • Metronidazole offers an effective short-term treatment for intestinal spirochetosis.