Postacute/Long COVID in Pediatrics: Development of a Multidisciplinary Rehabilitation Clinic and Preliminary Case

Amanda K Morrow1, Rowena Ng, Gray Vargas

  • 1From the Kennedy Krieger Institute, Baltimore, Maryland (AKM, RN, GV, DTJ, EH, NS, LAM); Department of Physical Medicine and Rehabilitation, Johns Hopkins School of Medicine, Baltimore, Maryland (AKM, LAM); Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore, Maryland (RN); and Department of Neurology, Johns Hopkins School of Medicine, Baltimore, Maryland (LAM).

Insights

Pediatric long COVID patients often experience fatigue, headaches, and cognitive issues. A multidisciplinary clinic model shows promise in addressing these persistent post-SARS-CoV-2 symptoms in children and adolescents.

Area of Science:

  • Pediatric Medicine
  • Infectious Diseases
  • Rehabilitation Medicine

Background:

  • Long-term effects of SARS-CoV-2 infection in children (pediatric long COVID) remain largely unknown.
  • There is a growing need for effective care models for pediatric patients experiencing persistent symptoms post-COVID-19.
  • Understanding the sequelae of SARS-CoV-2 in pediatric populations is crucial for developing targeted interventions.

Purpose of the Study:

  • To describe a pediatric multidisciplinary post-COVID-19 rehabilitation clinic model.
  • To present a case series of the initial cohort of patients managed at this clinic.
  • To characterize the common symptoms and outcomes in pediatric patients with postacute/long COVID.

Main Methods:

  • A consecutive sample of nine pediatric patients (<21 years) presenting to a multidisciplinary post-COVID-19 clinic was analyzed.
  • Data collected included presenting symptoms, quality-of-life measures, and neuropsychological testing results.
  • Comparison with healthy controls and analysis of preexisting conditions were performed.

Main Results:

  • The most frequent symptoms were fatigue (8/9), headaches (6/9), difficulty with schoolwork (6/8), brain fog (4/9), and dizziness (4/9).
  • Most patients reported decreased quality-of-life scores compared to healthy controls.
  • Neuropsychological testing revealed attention deficits in a subset, often associated with pre-existing attention or mood concerns; elevated depression and anxiety symptoms were also self-reported.

Conclusions:

  • Pediatric patients with postacute/long COVID exhibit diverse physical, cognitive, and mood symptoms.
  • A multidisciplinary rehabilitation approach offers a structured model of care for this emerging patient group.
  • This model aims to comprehensively address the multifaceted needs of children and adolescents with persistent post-COVID-19 symptoms.

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