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Postacute/Long COVID in Pediatrics: Development of a Multidisciplinary Rehabilitation Clinic and Preliminary Case
Amanda K Morrow1, Rowena Ng, Gray Vargas
1From the Kennedy Krieger Institute, Baltimore, Maryland (AKM, RN, GV, DTJ, EH, NS, LAM); Department of Physical Medicine and Rehabilitation, Johns Hopkins School of Medicine, Baltimore, Maryland (AKM, LAM); Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore, Maryland (RN); and Department of Neurology, Johns Hopkins School of Medicine, Baltimore, Maryland (LAM).
Insights
Pediatric long COVID patients often experience fatigue, headaches, and cognitive issues. A multidisciplinary clinic model shows promise in addressing these persistent post-SARS-CoV-2 symptoms in children and adolescents.
Area of Science:
- Pediatric Medicine
- Infectious Diseases
- Rehabilitation Medicine
Background:
- Long-term effects of SARS-CoV-2 infection in children (pediatric long COVID) remain largely unknown.
- There is a growing need for effective care models for pediatric patients experiencing persistent symptoms post-COVID-19.
- Understanding the sequelae of SARS-CoV-2 in pediatric populations is crucial for developing targeted interventions.
Purpose of the Study:
- To describe a pediatric multidisciplinary post-COVID-19 rehabilitation clinic model.
- To present a case series of the initial cohort of patients managed at this clinic.
- To characterize the common symptoms and outcomes in pediatric patients with postacute/long COVID.
Main Methods:
- A consecutive sample of nine pediatric patients (<21 years) presenting to a multidisciplinary post-COVID-19 clinic was analyzed.
- Data collected included presenting symptoms, quality-of-life measures, and neuropsychological testing results.
- Comparison with healthy controls and analysis of preexisting conditions were performed.
Main Results:
- The most frequent symptoms were fatigue (8/9), headaches (6/9), difficulty with schoolwork (6/8), brain fog (4/9), and dizziness (4/9).
- Most patients reported decreased quality-of-life scores compared to healthy controls.
- Neuropsychological testing revealed attention deficits in a subset, often associated with pre-existing attention or mood concerns; elevated depression and anxiety symptoms were also self-reported.
Conclusions:
- Pediatric patients with postacute/long COVID exhibit diverse physical, cognitive, and mood symptoms.
- A multidisciplinary rehabilitation approach offers a structured model of care for this emerging patient group.
- This model aims to comprehensively address the multifaceted needs of children and adolescents with persistent post-COVID-19 symptoms.
Abstract:
The long-term sequelae after SARS-CoV-2 infections in children is unknown. Guidance is needed on helpful models of care for an emerging subset of pediatric patients with postacute/long COVID who continue to experience persistent symptoms after initial COVID-19 diagnosis. Here, we describe a pediatric multidisciplinary post-COVID-19 rehabilitation clinic model as well as a case series of the initial cohort of patients who presented to this clinic. A consecutive sample of nine patients (pediatric patients <21 yrs of age) who presented to our clinic are included. The most common presenting symptoms were fatigue (8 of 9 patients), headaches (6 of 9), difficulty with schoolwork (6 of 8), "brain fog" (4 of 9), and dizziness/lightheadedness (4 of 9). Most patients had decreased scores on self-reported quality-of-life measures compared with healthy controls. In the patients who participated in neuropsychological testing, a subset demonstrated difficulties with sustained auditory attention and divided attention; however, most of these patients had preexisting attention and/or mood concerns. There were also some who self-reported elevated depression and anxiety symptoms. Pediatric patients with postacute/long COVID may present with a variety of physical, cognitive, and mood symptoms. We present a model of care to address these symptoms through a multidisciplinary rehabilitation approach.
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