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Updated: Oct 13, 2025
Using a Microfluidics Device for Mechanical Stimulation and High Resolution Imaging of C. elegans
Published on: February 19, 2018
Mechanosensation: Alpha-7 nAChR transduces sound signals in earless C. elegans
1Department of Neurobiology and Department of Neurosurgery of the First Affiliated Hospital, School of Medicine, Zhejiang University, Zhejiang 310053, China; NHC and CAMS Key Laboratory of Medical Neurobiology, MOE Frontier Science Center for Brain Research and Brain-Machine Integration, School of Brain Science and Brain Medicine, Zhejiang University, Hangzhou, Zhejiang 310053, China.
Abstract:
How do organisms without specialized auditory systems perceive and transduce sound? In this issue of Neuron, Iliff et al. (2021) investigate the functional mechanism of airborne sound sensation in Caenorhabditis elegans and highlight the crucial role of alpha-7 nicotinic acetylcholine receptor subunits in mechanotransduction.
