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New antibiotics from genetically engineered actinomycetes. I. 2-Norerythromycins, isolation and structural
J B McAlpine1, J S Tuan, D P Brown
1Pharmaceutical Products Division, Abbott Laboratories, Abbott Park, Illinois 60064.
The Journal of Antibiotics
|August 1, 1987
Abstract:
Novel macrolide antibiotics have been isolated from a genetically manipulated actinomycete. The major components produced have been isolated and identified as 2-norerythromycins A, B, C and D by mass spectrometry and extensive 1D and 2D NMR experiments.