Related Experiment Video
Updated: Oct 13, 2025

A Quantitative Sensory Testing Paradigm to Obtain Measures of Pain Processing in Patients Undergoing Breast Cancer Surgery
Published on: January 18, 2018
Evaluation of Postoperative Pain Management Using an Opioid-Sparing Protocol in Pediatric Surgical Patients
Jinhyun A Jung1, Kristi Higgins1, Patricia Lange2
1Department of Pharmacy, Virginia Commonwealth University Health System, Richmond, VA, USA.
Insights
An opioid-sparing protocol in pediatric surgery did not decrease inpatient opioid use but significantly reduced discharge opioid prescriptions. This highlights opportunities for optimizing pain management and prescribing practices in young surgical patients.
Area of Science:
- Pediatric Surgery
- Pain Management
- Pharmacology
Background:
- The U.S. has experienced rising rates of opioid misuse and overdose deaths since the 1990s.
- National initiatives aim to curb the opioid epidemic by limiting opioid prescriptions.
- An opioid-sparing protocol was implemented in pediatric surgical patients to address these concerns.
Purpose of the Study:
- To evaluate the impact of an opioid-sparing protocol on postoperative opioid prescribing patterns in pediatric surgical patients.
- To assess changes in opioid administration during hospitalization and at discharge.
- To analyze pain control and non-opioid analgesic use post-implementation.
Main Methods:
- Retrospective chart review of electronic medical records for patients aged 9-18.
- Analysis of laparoscopic appendectomy and cholecystectomy cases before and after protocol implementation.
- Collection of data on opioid administration, pain scores, and non-opioid analgesic use.
Main Results:
- Median inpatient opioid administration was 8 MMEs (pre) vs. 15 MMEs (post), P=0.310.
- Median discharge opioid prescriptions decreased from 150 MMEs (pre) to 60 MMEs (post), P=0.006.
- Patients reported mild pain scores in both pre- and post-implementation groups.
Conclusions:
- The opioid-sparing protocol did not alter inpatient opioid administration but reduced discharge prescriptions for pediatric surgical patients.
- Opioid administration during hospitalization for these procedures was minimal.
- Findings suggest further interventions and education are needed to optimize postoperative opioid prescribing.
Background:
Since the 1990s, the U.S. has faced increasing rates of opioid overuse, misuse, and overdose deaths. To combat the opioid epidemic, there have been national initiatives to limit prescribing of opioids. At our institution, we implemented an opioid-sparing protocol in pediatric surgical patients and sought to evaluate its impact on postoperative opioid prescribing patterns.
Methods:
A retrospective chart review of the electronic medical record was performed for 9- to 18-year-old patients who underwent a laparoscopic appendectomy or cholecystectomy before and after the implementation of an opioid-sparing protocol. Data on postoperative opioids administered during the hospitalization and prescribed at discharge, postoperative pain control, use of non-opioid analgesics, and safety were collected.
Results:
A total of 81 patient charts were analyzed. The median amount of opioids administered during hospitalization was 8 MMEs and 15 MMEs in the pre-implementation and post-implementation, respectively (P = 0.310). The median amount of opioids prescribed at discharge was 150 MMEs and 60 MMEs in the pre-implementation and post-implementation, respectively (P = 0.006). Patients reported mild pain scores throughout the hospitalization in both groups.
Discussion:
Among young patients who underwent laparoscopic appendectomy or cholecystectomy, the administration of opioids during hospitalization for postoperative pain was minimal. The opioid sparing protocol did not reduce the amount of inpatient postoperative opioids administered but found a decrease in the amount of opioids prescribed at discharge. The study findings identified further areas of intervention and education to optimize postoperative opioid prescribing after these common pediatric surgical procedures.
Related Concept Videos
Opioid Analgesics: Synthetic and Semisynthetic Opioids
Analgesia and Pain Management
Peripheral Artery Disease V: Postoperative Nursing Management
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Opioid Analgesics: Morphine and Other Natural Cogeners
Parenteral Anesthetics: Overview

