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Related Experiment Video

Updated: Oct 13, 2025

A Protocol for Using Gene Set Enrichment Analysis to Identify the Appropriate Animal Model for Translational Research

A Protocol for Using Gene Set Enrichment Analysis to Identify the Appropriate Animal Model for Translational Research

Published on: August 16, 2017

Translating Basic Research to Animal Agriculture.

George E Seidel¹

¹Animal Reproduction and Biotechnology Laboratory, Colorado State University, Fort Collins, Colorado, USA.

Annual Review of Animal Biosciences

|November 19, 2021

Summary

This summary is machine-generated.

Maintaining mammalian gamete and embryo viability through techniques like cryopreservation and artificial insemination has significantly advanced animal agriculture and assisted reproduction. These methods enable genetic improvement, cloning, and conservation efforts.

Keywords:

assisted reproduction autobiography biotechnology embryo in vitro oocyte sperm

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Area of Science:

Reproductive Biology
Animal Science
Biotechnology

Background:

Mammalian gamete and embryo viability in vitro is crucial for reproductive technologies.
Artificial insemination and embryo transfer are foundational techniques in animal breeding.

Purpose of the Study:

To review the development and application of in vitro mammalian gamete and embryo preservation techniques.
To highlight contributions to reproductive technologies for animal agriculture and conservation.

Main Methods:

In vitro culture and cryopreservation of gametes and embryos.
Artificial insemination and superovulation protocols.
Advanced reproductive technologies including sexing, in vitro fertilization, cloning, and genetic modification.

Main Results:

Established and refined techniques for maintaining mammalian gamete and embryo viability.
Demonstrated the efficacy of artificial insemination and embryo transfer for genetic improvement in animal populations.
Enabled advancements in human assisted reproduction, companion animal breeding, and endangered species conservation.

Conclusions:

In vitro gamete and embryo technologies have profoundly impacted animal agriculture, conservation, and human reproduction.
Continued innovation in reproductive biotechnology offers significant potential for future applications.
Collaboration and mentorship in this field have fostered personal and professional growth.