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Updated: Oct 13, 2025

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
Published on: June 16, 2020
ACR Appropriateness Criteria® Diffuse Lung Disease
, Stephen B Hobbs1, Jonathan H Chung2
1Vice-Chair, Informatics and Integrated Clinical Operations and Division Chief, Cardiovascular and Thoracic Radiology, University of Kentucky, Lexington, Kentucky.
This document provides guidelines for imaging diffuse lung diseases (DLDs), covering initial diagnosis, acute exacerbations, and routine follow-up. It emphasizes evidence-based criteria for appropriate imaging in interstitial lung disease evaluation.
Area of Science:
- Pulmonology
- Radiology
- Medical Imaging
Background:
- Diffuse lung diseases (DLDs), also known as interstitial lung diseases, comprise a wide spectrum of parenchymal lung disorders.
- Hundreds of etiologies exist, necessitating accurate diagnostic and management strategies.
- Imaging is crucial for DLD diagnosis and monitoring, often complemented by multidisciplinary discussions.
Framework:
- The guidelines address three key clinical scenarios: initial suspected DLD, acute exacerbations in confirmed DLD, and routine follow-up of stable DLD.
- These evidence-based recommendations are derived from the American College of Radiology Appropriateness Criteria.
- Methodologies like RAND/UCLA and GRADE inform the appropriateness ratings for imaging procedures.
Implementation:
- The guidelines aim to standardize the evaluation of diffuse lung diseases through imaging.
- They provide a framework for selecting the most appropriate imaging studies based on clinical presentation.
- Expert opinion may be used to supplement evidence in cases with limited data.
Implications:
- Standardized imaging guidelines can improve diagnostic accuracy and patient management for diffuse lung diseases.
- Appropriate use of imaging may lead to more efficient healthcare resource utilization.
- These guidelines support clinicians in navigating the complex landscape of interstitial lung disease diagnosis and follow-up.
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