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Updated: Oct 12, 2025

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Treatment of Ankle Osteoarthritis with Total Ankle Replacement Through a Lateral Transfibular Approach
Published on: January 24, 2018
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Operative Ankle Fractures in Complicated Diabetes: Outcomes of Prolonged Non-Weightbearing
Anthony G Brutico1, Ellianne M Nasser2, Joseph M Brutico3
1Principal Investigator, Regional Foot and Ankle Center, Dunmore, PA.
Summary
Prolonged non-weightbearing may reduce complications in diabetic ankle fractures. Higher creatinine levels significantly increase complication risk in these patients, suggesting it as an independent risk factor.
Area of Science:
- Orthopedic Surgery
- Diabetology
- Podiatry
Background:
- Diabetes mellitus significantly elevates the risk of postoperative complications, including infection and wound dehiscence, particularly in ankle fracture cases.
- Complicated diabetic ankle fractures require careful management to mitigate adverse outcomes.
Purpose of the Study:
- To compare postoperative complication rates in complicated diabetic ankle fractures based on weightbearing status.
- To investigate the impact of prolonged non-weightbearing and augmented fixation on surgical outcomes.
Main Methods:
- Retrospective review of 90 surgically treated complicated diabetic ankle fractures.
- Analysis of weightbearing status (prolonged non-weightbearing defined as ≥ 8 weeks), augmented fixation, and postoperative complications.
- Statistical analysis to identify risk factors, including HbA1c and creatinine levels.
Main Results:
- 36.7% of patients experienced postoperative complications.
- Prolonged non-weightbearing showed a trend towards fewer complications (29.2% vs 39.4%), associated with higher HbA1c levels.
- Increased creatinine levels (one-unit increase) correlated with a 3.15-fold higher risk of complications (p=0.01).
Conclusions:
- Prolonged non-weightbearing may be beneficial for reducing complications in complicated diabetic ankle fractures, though not statistically significant in this study.
- Creatinine level is identified as an independent risk factor for postoperative complications in this patient population.
- Further research is warranted to optimize management strategies for diabetic ankle fractures.
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