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Related Experiment Video

Updated: Oct 12, 2025

Adjunctive Diode Laser Therapy and Probiotic Lactobacillus Therapy in the Treatment of Periodontitis and Peri-Implant Disease
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Adjunctive Diode Laser Therapy and Probiotic Lactobacillus Therapy in the Treatment of Periodontitis and Peri-Implant Disease

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Probiotics-Mediated Bioconversion and Periodontitis.

Yewon Lee1, Yohan Yoon1,2, Kyoung-Hee Choi3

  • 1Department of Food and Nutrition, Sookmyung Women's University, Seoul 04310, Korea.

Food Science of Animal Resources
|November 19, 2021
PubMed
Summary
This summary is machine-generated.

Probiotics-mediated bioconversion (PMB) metabolites from fermented foods show promise for treating periodontitis. These natural compounds offer an alternative to antibiotics, potentially reducing drug resistance and supporting oral health.

Keywords:
bioconversionperiodontitisprobioticsprobiotics-mediated bioconversion

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Area of Science:

  • Microbiology
  • Periodontology
  • Biochemistry

Background:

  • Periodontitis is a chronic inflammatory oral disease leading to tooth tissue destruction.
  • Current treatments like antibiotics face challenges due to drug resistance and disruption of beneficial oral bacteria.
  • Probiotics-mediated bioconversion (PMB) metabolites derived from fermented foods offer potential therapeutic benefits.

Purpose of the Study:

  • To review recent studies on the relationship between periodontitis and PMB metabolites.
  • To classify the efficacy of major PMB metabolites in managing periodontitis.
  • To explore PMB metabolites as potential alternatives to antibiotics for periodontitis treatment.

Main Methods:

  • Literature review of studies investigating PMB metabolites and periodontitis.
  • Analysis of reported bioactivities of PMB metabolites, including antioxidant and anti-inflammatory effects.
  • Classification of PMB metabolite efficacy based on existing research.

Main Results:

  • PMB metabolites exhibit various beneficial activities, including antioxidant, anti-inflammatory, and antimicrobial properties.
  • Emerging research suggests PMB metabolites may be effective in managing periodontitis.
  • Fermented milk and other PMB metabolites are explored as potential antibiotic substitutes.

Conclusions:

  • PMB metabolites demonstrate therapeutic potential for periodontitis.
  • Further research is required to validate the clinical efficacy of PMB metabolites in periodontitis treatment.
  • PMB metabolites represent a promising avenue for novel periodontitis therapies, potentially overcoming antibiotic resistance issues.