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Updated: Oct 12, 2025

Surgical Swine Model of Chronic Cardiac Ischemia Treated by Off-Pump Coronary Artery Bypass Graft Surgery
Published on: March 27, 2018
[Chronic coronary syndrome]
Tine Glavind Bülow Pedersen, Jens Sundbøll, Søren Warberg Becker
1kpryds@clin.au.dk.
Insights
The 2019 European Society of Cardiology guidelines introduced chronic coronary syndrome (CCS) for stable coronary artery disease, emphasizing non-invasive diagnostics like CT angiography. Treatment decisions for CCS, particularly antithrombotic therapy after revascularization, require individualized risk assessment.
Area of Science:
- Cardiology
- Cardiovascular Medicine
Background:
- The term "stable coronary artery disease" has been updated to "chronic coronary syndrome" (CCS) in the 2019 European Society of Cardiology guidelines.
- Significant shifts in diagnostic, therapeutic, and preventive strategies for CCS are highlighted.
Purpose of the Study:
- To summarize the key changes in the diagnosis, treatment, and prevention of chronic coronary syndrome (CCS) as per the 2019 ESC guidelines.
- To underscore the evolving role of non-invasive imaging and individualized antithrombotic therapy in CCS management.
Main Methods:
- Review of the 2019 European Society of Cardiology guidelines concerning chronic coronary syndrome.
- Analysis of diagnostic advancements, focusing on non-invasive imaging modalities.
- Evaluation of current antithrombotic treatment strategies based on thrombosis and bleeding risks.
Main Results:
- Increased emphasis on non-invasive diagnostic tools, notably coronary CT angiography, for CCS evaluation.
- Antithrombotic treatment selection and duration should be personalized, considering individual thrombosis and bleeding risks.
- These principles are particularly crucial in patients who have undergone coronary revascularization.
Conclusions:
- The updated guidelines for chronic coronary syndrome necessitate a paradigm shift towards personalized, risk-stratified management.
- Non-invasive imaging and tailored antithrombotic therapy are central to optimizing outcomes in CCS patients.
Abstract:
In the 2019 European Society of Cardiology guidelines, chronic coronary syndrome (CCS) was introduced as a new term for stable coronary artery disease. Diagnosis, treatment and prevention of CCS have undergone major changes. In the diagnostic management of CCS, there is increased focus on non-invasive imaging modalities, including coronary CT angiography. Based on the risk of thrombosis and bleeding, choice and duration of antithrombotic treatment should be individualised, especially following coronary revascularisation.
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