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Beyond the Liver Function Tests: A Radiologist's Guide to the Liver Blood Tests
Brandon M Metra1, Flavius F Guglielmo1, Dina L Halegoua-DeMarzio1
1From the Departments of Radiology (B.M.M., F.F.G., D.G.M.) and Internal Medicine (D.L.H.D., J.M.C.), Division of Gastroenterology and Hepatology, Thomas Jefferson University, 132 S 10th St, Main Bldg, Philadelphia, PA 19107.
Summary
Liver blood tests help identify liver disease patterns like hepatocellular or cholestatic. Integrating these test results with imaging aids radiologists in accurate hepatobiliary disease diagnosis.
Area of Science:
- Hepatology
- Radiology
- Clinical Chemistry
Background:
- Liver blood tests are crucial for diagnosing and managing hepatobiliary diseases.
- Abnormal results often prompt imaging studies like ultrasound, CT, or MRI.
- Hepatobiliary diseases typically present as hepatocellular or cholestatic patterns on liver blood tests.
Purpose of the Study:
- To review major liver blood tests and their patterns.
- To provide an approach for recognizing common hepatobiliary disease patterns.
- To discuss the integration of liver blood tests with imaging for diagnosis.
Main Methods:
- Review of major liver blood tests.
- Categorization of diseases into hepatocellular and cholestatic patterns.
- Correlation of test abnormalities with imaging findings.
Main Results:
- Liver blood tests exhibit characteristic patterns for hepatocellular and cholestatic diseases.
- Imaging findings combined with test patterns aid in differential diagnosis.
- Elastography may be used for evaluating chronic hepatitis and fibrosis.
- Liver blood tests and imaging are vital in post-hepatic transplant care.
Conclusions:
- Integrating liver blood test patterns with imaging findings enhances diagnostic accuracy for hepatobiliary diseases.
- This combined approach is particularly useful when imaging alone is inconclusive.
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