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Updated: Oct 12, 2025

Prehospital Thrombolysis: A Manual from Berlin
Published on: November 26, 2013
Shifting acute stroke management to the prehospital setting
Martin Ebinger1,2, Heinrich J Audebert1,3
1Center for Stroke Research Berlin, Charité - Universitätsmedizin Berlin.
Purpose Of Review:
The earlier the treatment, the better the outcomes after acute ischemic stroke. Optimizing prehospital care bears potential to shorten treatment times. We here review the recent literature on mothership vs. drip-and-ship as well as mobile stroke unit concepts.
Recent Findings:
Mobile stroke units result in the shortest onset-to-treatment times in mostly urban settings.
Summary:
Future research should focus on further streamlining processes around mobile stroke units, especially improving dispatch algorithms and improve referral for endovascular therapy.
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