Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Self-Locking Screw01:16

Self-Locking Screw

1.9K
A square-threaded screw jack is a mechanical device widely used for lifting heavy loads or applying considerable force. One of the key features that can make a screw jack more effective and reliable is its self-locking capability.
A square-threaded screw jack carrying a load is considered self-locking if the screw retains its position even after the moment applied to it is removed.
1.9K
Wedges01:24

Wedges

1.3K
A wedge is a simple machine that serves various purposes, such as adjusting the elevation of structural or mechanical parts, providing stability for heavy objects, and splitting a body into two parts. This versatile tool can amplify an applied force, making it easier to manipulate large or heavy objects.
Consider using a wedge to lift a heavy slab. Here, the wedge functions by converting the applied force into a much larger force directed almost perpendicular to the initial force. This...
1.3K
Second Uniqueness Theorem01:16

Second Uniqueness Theorem

1.2K
Consider a region consisting of several individual conductors with a definite charge density in the region between these conductors. The second uniqueness theorem states that if the total charge on each conductor and the charge density in the in-between region are known, then the electric field can be uniquely determined.
In contrast, consider that the electric field is non-unique and apply Gauss's law in divergence form in the region between the conductors and the integral form to the...
1.2K
Design Example: Forces in Sluice Gate01:11

Design Example: Forces in Sluice Gate

1.7K
In hydraulic engineering, sluice gates are essential for managing water flow through channels, reservoirs, and irrigation systems. Sluice gates, acting as vertical barriers, regulate water by adjusting the gate's opening height, which changes the velocity and pressure of water flowing beneath the gate. Understanding the forces involved is crucial to designing sluice gates that can withstand dynamic pressure differences, especially when the gate is closed or partially open.
Key variables in...
1.7K
Frictional Forces on Screws01:17

Frictional Forces on Screws

1.3K
Screws are characterized by a helical ridge known as a thread wrapped around a cylindrical shaft. They are commonly used as fasteners to hold objects together or to transmit power and motion in machines. One type of screw that is particularly useful for transmitting power is the square-threaded screw.
A jack with a square-threaded screw is a mechanical device used to lift heavy loads by applying a force at its handle. When the force is applied, the screw turns, raising the load. The screw can...
1.3K
Pascal's Law01:04

Pascal's Law

9.6K
In 1653, the French philosopher and scientist Blaise Pascal published "Treatise on the Equilibrium of Liquids," which discussed the principles of static fluids. A static fluid is a fluid that is not in motion. When a fluid is not flowing, we say that the fluid is in static equilibrium. If the fluid is water, we say it is in hydrostatic equilibrium. For a fluid in static equilibrium, the net force on any part of the fluid must be zero; otherwise, the fluid will start to flow. Pascal...
9.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Phosphatidylserine and RhoB connect PI4P and PA metabolism to maintain plasma membrane identity.

The Journal of cell biology·2026
Same author

Singlet oxygen spills sterol secrets.

Nature chemical biology·2026
Same author

Structural innovation in the evolution of plant chemical defense.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

Cullin-3 adaptor SHKBP1 inhibits SQSTM1/p62 oligomerization and Keap1 sequestration.

The Journal of cell biology·2026
Same author

Membrane editing with proximity labeling reveals regulators of lipid homeostasis.

Nature chemical biology·2026
Same author

Phosphatidylserine and RhoB connect phosphatidylinositol 4-phosphate and phosphatidic acid metabolism at the plasma membrane.

bioRxiv : the preprint server for biology·2025
Same journal

Cryo-EM sheds light on the mechanism of human telomerase inhibition by BIBR1532.

Nature chemical biology·2026
Same journal

Artificial metalloenzymes in complex biological environments.

Nature chemical biology·2026
Same journal

Allosteric disordering of eIF2B regulates the integrated stress response.

Nature chemical biology·2026
Same journal

A tail of two ligases.

Nature chemical biology·2026
Same journal

Non-canonical cytochrome P450 enzymes expand the diversity of bacterial hemoproteins.

Nature chemical biology·2026
Same journal

Image-guided activation of drugs with electromagnetic radiation.

Nature chemical biology·2026
See all related articles

Related Experiment Video

Updated: Oct 12, 2025

Design and Synthesis of a Reconfigurable DNA Accordion Rack
07:44

Design and Synthesis of a Reconfigurable DNA Accordion Rack

Published on: August 15, 2018

7.2K

There is a lock for every key

Weizhi Yu1,2, Jeremy M Baskin3,4

  • 1Department of Chemistry and Chemical Biology, Cornell University, Ithaca, NY, USA.

Nature Chemical Biology
|November 20, 2021
PubMed
Summary

No abstract available in PubMed .

More Related Videos

Treatment with Locking Intramedullary Nailing for Intertrochanteric Fracture of the Femur Utilizing a New Awl with a Distal Positioner
04:41

Treatment with Locking Intramedullary Nailing for Intertrochanteric Fracture of the Femur Utilizing a New Awl with a Distal Positioner

Published on: June 6, 2025

302
An Intramedullary Locking Nail for Standardized Fixation of Femur Osteotomies to Analyze Normal and Defective Bone Healing in Mice
07:41

An Intramedullary Locking Nail for Standardized Fixation of Femur Osteotomies to Analyze Normal and Defective Bone Healing in Mice

Published on: November 13, 2016

13.6K

Related Experiment Videos

Last Updated: Oct 12, 2025

Design and Synthesis of a Reconfigurable DNA Accordion Rack
07:44

Design and Synthesis of a Reconfigurable DNA Accordion Rack

Published on: August 15, 2018

7.2K
Treatment with Locking Intramedullary Nailing for Intertrochanteric Fracture of the Femur Utilizing a New Awl with a Distal Positioner
04:41

Treatment with Locking Intramedullary Nailing for Intertrochanteric Fracture of the Femur Utilizing a New Awl with a Distal Positioner

Published on: June 6, 2025

302
An Intramedullary Locking Nail for Standardized Fixation of Femur Osteotomies to Analyze Normal and Defective Bone Healing in Mice
07:41

An Intramedullary Locking Nail for Standardized Fixation of Femur Osteotomies to Analyze Normal and Defective Bone Healing in Mice

Published on: November 13, 2016

13.6K