Related Experiment Video
Updated: Jul 24, 2026

Modeling Oral-Esophageal Squamous Cell Carcinoma in 3D Organoids
Published on: December 23, 2022
[Esophageal squamous papilloma - a case report]
Konrad Pielaciński1, Agata Pielacińska2, Monika Prochorec-Sobieszek3
1Department of General, Oncologic and Metabolic Surgery, Institute of Hematology and Transfusion Medicine, Warsaw, Poland.
Esophageal squamous cell papillomas (ESPs) are rare benign lesions. Endoscopic resection effectively removes these papillomas, with esophagogastroduodenoscopy suitable for surveillance.
Area of Science:
- Gastroenterology
- Oncology
- Pathology
Background:
- Esophageal squamous cell papilloma (ESP) is a rare, typically asymptomatic benign lesion.
- Larger or multiple ESPs can cause symptoms like dysphagia and bleeding.
- The malignant potential of ESPs remains unknown, lacking established endoscopic surveillance guidelines.
Observation:
- A 65-year-old woman presented with epigastric pain and heartburn.
- Esophagogastroduodenoscopy revealed multiple papillomatous structures in the esophagus.
- Initial biopsy confirmed squamous cell papilloma, with no HPV detected.
Findings:
- Endoscopic resection successfully removed all identified ESPs.
- Histopathology confirmed ESPs without HPV presence in resected specimens.
- A six-month follow-up esophagogastroduodenoscopy showed no recurrence.
Implications:
- Endoscopic resection is an effective treatment for esophageal squamous cell papillomas.
- Esophagogastroduodenoscopy can serve as a surveillance tool for ESPs.
- Further research is needed to clarify the malignant potential of ESPs.
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