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Related Concept Videos

Bone Disorders01:29

Bone Disorders

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Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
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What is the Skeletal System?01:02

What is the Skeletal System?

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Overview
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Role of Vitamins in Maintaining Bone Health01:25

Role of Vitamins in Maintaining Bone Health

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The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
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Hormones and Bone Tissue01:17

Hormones and Bone Tissue

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The endocrine system produces and secretes hormones, which interact with the skeletal system. These hormones control bone growth, maintain bone once it is formed, and remodel it.
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
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The Functions of the Skeletal System01:22

The Functions of the Skeletal System

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The most apparent functions of the skeletal system are support, protection, and movement. However, bone tissue also performs several other critical metabolic functions. For one, the bone matrix acts as a reservoir for a number of minerals important to the functioning of the body, especially calcium and phosphorus. These minerals, present in the bone tissue, can be released back into the bloodstream when required. Calcium ions, for example, are essential for muscle contractions and controlling...
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Bone Remodeling01:40

Bone Remodeling

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Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
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Estrogen-Like Effect of Bazi Bushen Capsule in Ovariectomized Rats
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Osteoporosis: Common Side Effect.

Marybeth Singer1

  • 1Tufts Medical Center.

Clinical Journal of Oncology Nursing
|November 20, 2021
PubMed
Summary

Osteoporosis is a common metabolic bone disease causing low bone mass and tissue deterioration. Osteopenia is a less severe form of bone loss, with current osteoporosis care standards evolving with evidence-based practice.

Area of Science:

  • Bone metabolism and osteoporosis research.
  • Clinical practice guidelines for bone density disorders.

Background:

  • Osteoporosis is the most prevalent metabolic bone disease.
  • Characterized by diminished bone mineral density and microarchitectural deterioration.
  • Osteopenia represents a milder stage of bone loss compared to osteoporosis.

Purpose of the Study:

  • To summarize current standards of care for osteoporosis.
  • To differentiate between osteopenia and osteoporosis based on bone density.

Main Methods:

  • Review of emerging evidence-based practices in osteoporosis management.
  • Analysis of diagnostic criteria for osteopenia and osteoporosis.

Main Results:

  • Current osteoporosis care is guided by evolving evidence-based practices.
Keywords:
bone losscancerlong-term symptomsosteoporosissurvivorship care

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  • Osteopenia is defined as bone density lower than normal, preceding osteoporosis.

    • Conclusions:

    • Understanding the spectrum of bone loss, from osteopenia to osteoporosis, is crucial.
    • Adherence to evidence-based practice is essential for optimal osteoporosis management.