Clinical evaluation of bempedoic acid for the treatment of hyperlipidaemia
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Published on: April 7, 2023
Maurizio Averna1, Claudio Bilato2, Giorgio Sesti3
1Department of Health Promotion Sciences Maternal and Infantile Care, Internal Medicine and Medical Specialities, University of Palermo, Palermo, Italy.
Abstract:
Bempedoic acid (BA) is a novel first-in-class oral lipid-lowering therapy. BA has been approved by the European Medicinal Agency and Food and Drug Administration and has been commercialised throughout Europe since the end of 2020 as an add-on therapy in patients at high/very-high cardiovascular risk that are not at LDL-C goals with current lipid-lowering treatments. Recently, Italian lipid management experts gathered to discuss several open questions on BA characteristics and BArelated practical clinical issues. The panel permitted collection of its opinions in a ten Q&A format.
Aim:
The aim of this viewpoint is to discuss and answer several open questions on BA characteristics and BA-related practical clinical issues.
Data Synthesis:
The data includes main phase III studies, subanalysis and meta-analysis on BA.
Conclusions:
The panel permitted collection of its opinions in a ten Q&A format.
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