[Persistent COVID-19 syndrome. A narrative review]

Area of Science:

• Infectious Diseases
• Virology
• Public Health

Context:

• The COVID-19 pandemic, caused by SARS-CoV-2, has led to a growing concern regarding persistent symptoms long after the acute infection.
• Persistent COVID-19 syndrome, or long COVID, affects individuals regardless of initial infection severity, including mild and asymptomatic cases.
• The heterogeneous and multisystemic nature of long COVID necessitates a multidisciplinary approach to patient care.

Purpose:

• To review the clinical manifestations of persistent COVID-19 syndrome.
• To outline current strategies for the management and follow-up of patients experiencing long COVID.
• To consolidate existing medical literature on the evolving understanding of long COVID.

Summary:

• Persistent COVID-19 syndrome is characterized by a wide range of symptoms that can emerge weeks or months after the initial SARS-CoV-2 infection.
• These symptoms are multisystemic and can significantly impact a patient's quality of life, work, and social interactions.
• Management requires a coordinated, multidisciplinary strategy due to the complexity and varied presentation of the condition.

Impact:

• Long COVID can profoundly affect patients' quality of life and their ability to engage in work and social activities.
• Understanding the sequelae of COVID-19 is crucial for developing effective long-term healthcare strategies.
• This review aims to inform healthcare professionals about the clinical picture and management of persistent COVID-19 syndrome.