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A Narrative Review of Existing Options for COVID-19-Specific Treatments

Wasey Ali Yadullahi Mir1, Abdul Hasan Siddiqui2, Gautam Valecha2

  • 1Department of Internal Medicine, Mount Sinai Hospital, Chicago, IL, USA.

Advances in Virology
|November 22, 2021
PubMed

Insights

This review summarizes current COVID-19 treatments, exploring their mechanisms, roles, and side effects. It aims to provide an evidence-based overview of therapeutic options for the novel coronavirus disease.

Area of Science:

  • Infectious Diseases
  • Pharmacology
  • Virology

Background:

  • The COVID-19 pandemic, caused by SARS-CoV-2, has led to significant global morbidity and mortality.
  • Limited effective treatment options are currently available for COVID-19.
  • There is an urgent need to explore and evaluate therapeutic strategies targeting the multifaceted pathology of the disease.

Purpose of the Study:

  • To review and summarize existing treatment options for COVID-19.
  • To elucidate the mechanisms of action, clinical roles, and potential side effects of these therapies.
  • To provide an evidence-based overview for clinicians and researchers.

Main Methods:

  • Comprehensive literature search of published studies on COVID-19 treatments.
  • Systematic review and synthesis of data on drug mechanisms, efficacy, and safety.
  • Analysis of current evidence regarding therapeutic interventions.

Main Results:

  • Multiple drugs are in use, but a limited number demonstrate definitive clinical efficacy.
  • Various therapeutic targets are being explored, addressing different pathologic aspects of COVID-19.
  • Detailed information on the mechanism, roles, and side effects of existing treatments has been compiled.

Conclusions:

  • The current landscape of COVID-19 treatments is evolving, with ongoing research into novel therapeutic agents.
  • Understanding the mechanism, roles, and side effects of existing drugs is crucial for effective patient management.
  • Further research is needed to identify and validate optimal treatment strategies for COVID-19.

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