Related Experiment Video
Updated: Oct 12, 2025

Flexible Colonoscopy in Mice to Evaluate the Severity of Colitis and Colorectal Tumors Using a Validated Endoscopic Scoring System
Published on: October 16, 2013
Ischemic Colitis Caused by Bowel Preparation for Colonoscopy
Takuji Kawamura1, Naokuni Sakiyama1, Kiyohito Tanaka1
1Department of Gastroenterology, Kyoto Second Red Cross Hospital, Kyoto, Japan.
Elderly patients (≥ 75 years) and those with constipation undergoing colonoscopy bowel preparation face increased risk of ischemic colitis. Stronger preparation methods heighten this risk, necessitating careful patient selection and monitoring.
Area of Science:
- Gastroenterology
- Colorectal Surgery
- Internal Medicine
Background:
- Ischemic colitis is a potential adverse event during colonoscopy preparation.
- Understanding its incidence and risk factors is crucial for patient safety.
Purpose of the Study:
- To determine the incidence of ischemic colitis following bowel preparation for colonoscopy.
- To identify independent risk factors associated with this complication.
Main Methods:
- A retrospective, single-center observational study included 14,924 outpatients undergoing colonoscopy.
- Standardized split bowel preparation protocols were used.
- Data were analyzed from electronic medical records and endoscopy databases.
Main Results:
- The incidence of ischemic colitis was 0.09% (14 patients).
- Independent risk factors identified were age ≥ 75 years (OR: 3.64) and strong bowel preparation for constipated patients (OR: 4.27).
Conclusions:
- Age 75 years and older and strong bowel preparation in constipated individuals are significant risk factors for ischemic colitis.
- Clinicians should exercise caution with bowel preparation for elderly patients and those with constipation before colonoscopy.
Related Concept Videos
Inflammatory Bowel Disease I: Ulcerative Colitis
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Endoscopic Procedures II: Colonoscopy
Inflammatory Bowel Disease V: Surgical Management
Here are some common surgical interventions for IBD:
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy
Radionuclide Testing
Radionuclide testing is a sophisticated medical technique for assessing gastrointestinal motility. It focuses on gastric emptying and colonic transit time. Radioactive markers track the movement of food through the digestive system, providing insights into gastrointestinal disorders.
In gastric emptying studies, a meal's liquid and...
Drugs for Treatment of Ulcerative Colitis in IBD

