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Related Experiment Video

Updated: Oct 12, 2025

Generating Acute and Chronic Experimental Models of Motor Tic Expression in Rats

Generating Acute and Chronic Experimental Models of Motor Tic Expression in Rats

Published on: May 27, 2021

Is Tourette syndrome a rare condition?

Andreas Hartmann¹, Natalia Szejko^2,3, Nanette Mol Debes⁴

¹National Reference Center for Tourette Syndrome, Department of Neurology, Groupe Hospitalier Pitié-Salpêtrière, Paris, 75013, France.

|November 23, 2021

Summary

Tourette syndrome is not rare, but this opinion article argues it is an orphan or neglected disease. Further research and support are needed for this underrecognized neurological disorder.

Keywords:

Tourette syndrome orphan disease rare disease tics

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Area of Science:

Neurology
Genetics

Background:

Tourette syndrome (TS) is a complex neurological disorder characterized by motor and vocal tics.
While not rare based on prevalence, TS often faces challenges in research funding and clinical attention.

Purpose of the Study:

To argue that Tourette syndrome, despite its prevalence, should be classified as an orphan or neglected disease.
To highlight the disparity between TS prevalence and its recognition in research and clinical practice.

Main Methods:

This is an opinion article, not based on empirical data.
The argument is built on the concept of disease neglect and orphan status.

Main Results:

The article posits that Tourette syndrome meets criteria for neglect or orphan status.
This classification is based on factors beyond mere prevalence.

Conclusions:

Tourette syndrome warrants greater attention and resources akin to other orphan diseases.
Reclassifying TS could stimulate research and improve patient outcomes.