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Regenerative Therapy by Suprachoroidal Cell Autograft in Dry Age-related Macular Degeneration: Preliminary In Vivo Report

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Unilateral Anophthalmic Socket Reconstruction With Dermis Fat Graft.

Saba Alkhairy¹, Mahad M Baig¹, Usman A Pasha¹

¹Ophthalmology, Dow University of Health Sciences, Dow International Medical College, Karachi, PAK.

|November 22, 2021

Summary

This study details a successful surgical repair for a congenital anophthalmic socket using a dermis fat graft (DFG) and a mucous membrane graft. The procedure restored cosmetic appearance and addressed medical concerns for a 15-year-old patient.

Keywords:

conjunctival insufficiency cosmetic decreased orbital volume dermis fat graft isolated anophthalmia mucous membrane graft orbital volume prosthetic eye reconstruction unilateral anophthalmia

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Published on: October 31, 2012

Area of Science:

Ophthalmology
Plastic Surgery
Regenerative Medicine

Background:

Congenital anophthalmia, characterized by the absence of an ocular globe, presents significant cosmetic and functional challenges.
Anophthalmic sockets often exhibit reduced orbital volume and shallow conjunctival fornices, complicating prosthetic eye fitting.

Observation:

A 15-year-old female presented with a cosmetically disfigured right eye since birth, diagnosed as an anophthalmic socket.
Physical examination revealed a lack of ocular tissue, short conjunctival fornices (particularly inferiorly), and decreased orbital volume.

Findings:

A dermis fat graft (DFG) from the gluteal region was used to augment orbital volume and was sutured into the anophthalmic socket.
A secondary surgery utilizing a mucous membrane graft from the lower lip deepened the inferior fornix.
The combined surgical interventions successfully addressed cosmetic and medical concerns, enabling prosthetic eye placement.

Implications:

Dermis fat grafts (DFGs) are effective for increasing orbital volume in anophthalmic sockets.
Combined grafting techniques, including mucous membrane grafts, can successfully reconstruct shallow fornices.
This reconstructive approach significantly improves cosmetic outcomes and patient quality of life in anophthalmia cases.
Meta_The surgical repair of an anophthalmic socket using dermis fat and mucous membrane grafts offers a viable solution for cosmetic and functional restoration.