Invasive Aspergillus flavus sinusitis in an immunocompetent patient using intranasal cocaine

Area of Science:

• Mycology
• Infectious Diseases
• Otolaryngology

Background:

• Invasive fungal sinusitis is a severe infection, typically seen in immunocompromised patients.
• Aspergillus species are common fungal pathogens causing sinusitis.

Observation:

• A 33-year-old immunocompetent male presented with chronic facial and nasal pain unresponsive to antibiotics.
• Diagnosis of invasive Aspergillus sinusitis was established after prolonged symptoms.

Findings:

• The patient achieved successful recovery through surgical debridement and voriconazole treatment.
• This case underscores that invasive fungal sinusitis can occur in immunocompetent hosts.

Implications:

• Early diagnosis and combined surgical and antifungal therapy are crucial for managing invasive fungal sinusitis.
• Clinicians should consider invasive fungal sinusitis in immunocompetent patients with refractory sinonasal symptoms.