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Morphology of the ascending aorta: a study on 114 Chinese patients
Lei Liu1, Wei Wang2, Qingsheng Lu1
1Department of Vascular Surgery, Changhai Hospital, Second Military Medical University, CPLA, 168 Changhai Road, Shanghai 200433, China.
Insights
Ascending aortic dissection alters aorta curvature, making it straighter and steeper. Dissection entry points near valves and involvement of branch arteries significantly impact dissection extent.
Area of Science:
- Cardiovascular Surgery
- Medical Imaging
- Anatomical Pathology
Background:
- Ascending aortic dissection is a life-threatening condition requiring detailed morphological understanding.
- Previous studies have not fully elucidated the specific geometric and positional characteristics of ascending aortic dissections.
Observation:
- A novel assessment method was employed to analyze the morphology of 114 patients with ascending aortic dissection.
- Significant differences in aortic curvature were observed, with dissected aortas being straighter and steeper.
Findings:
- Dissection entry points near the aortic sinus, particularly at the 10 and 1-2 o'clock positions, were common, often fusiform in shape.
- Dissections involving branch arteries extended further distally compared to those that did not.
- A straighter and steeper ascending aorta (R: 59.70 ± 10.27 mm) was associated with dissection compared to controls (R: 47.46 ± 6.40 mm).
Implications:
- Understanding these morphological features can aid in surgical planning and risk stratification for ascending aortic dissection.
- The study highlights key anatomical correlations that may influence the progression and management of the disease.
- Further research into the biomechanics of dissected aortas could refine treatment strategies.
Abstract:
Purpose: This study aimed to investigate the morphological characteristics of ascending aortic dissection in detail. Materials and Methods: The ascending aorta was morphologically assessed in a consecutive series of patients between January 2009 and October 2014. A new assessment and evaluation method was used to describe 114 patients with ascending aortic dissection. Results: A large difference was found in the degree of curvature between the ascending aorta with and without dissection. The shape of the former was straighter and steeper (control group R, 47.46 ± 6.40 mm; experimental group R, 59.70 ± 10.27 mm, P < 0.001). In the case of aortic dissection involving the valves, the proximal edge of the first entry was obviously close to the aortic sinus. The orientation of the entries was mainly around the 10 o'clock and 1-2 o'clock positions, and most of their shapes were fusiform (111; 70.02%). The distance of the distal extending dissection was associated with cases involving the branch arteries (involving three branches 441.40 ± 101.13 mm vs 159.85 ± 131.86 mm in others, P < 0.001). Conclusion: The morphological features of the ascending aorta after dissection and the correlations among dissections, entries, and related factors were found.
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