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Updated: Oct 12, 2025

Porcine Liver Transplantation Without Veno-Venous Bypass As an Extended Criteria Donor Model
Published on: August 17, 2022
Direct transmesenteric venous interventions in the acute post liver transplant setting
Keshav Anand1, Luis Garza1, Glenn Halff1
1UT Health San Antonio Long School of Medicine, 7703 Floyd Curl Dr, San Antonio, TX, 78229, USA.
Portal vein thrombosis after liver transplant can cause graft failure. Direct superior mesenteric vein (SMV) access by interventional radiology (IR) and surgery teams successfully removed thrombus, preserving the graft.
Area of Science:
- Interventional Radiology
- Transplant Surgery
- Hepatology
Background:
- Portal venous thrombosis and stenosis are critical complications impacting liver transplant graft survival.
- While surgical options exist, interventional radiology (IR) offers promising venous interventions.
Observation:
- A 69-year-old female with non-alcoholic steatohepatitis cirrhosis developed portal vein thrombus post-liver transplant.
- Collaboration between transplant surgery and IR was crucial for managing this complication.
Findings:
- Successful thrombus removal was achieved through direct superior mesenteric vein (SMV) access.
- This approach facilitated a direct route to the thrombus, minimized damage to liver parenchyma, and ensured effective hemostasis.
Implications:
- Direct SMV access presents a valuable strategy for managing post-transplant portal vein thrombus.
- This minimally invasive technique enhances graft survival and patient outcomes in liver transplantation.
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