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Updated: Oct 12, 2025

Endoscopic Injection Sclerotherapy Assisted by Cyanoacrylate and Clips for Gastroesophageal Varices
Published on: June 13, 2025
Coil-assisted retrograde transvenous obliteration for gastric varices in a Chinese case
Pengxu Ding1,2, Chao Liu1, Xinwei Han1
1Department of Intervention, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Insights
Coil-assisted retrograde transvenous obliteration (CARTO) offers a promising alternative for treating gastric varices bleeding in liver cirrhosis patients. This modified technique avoids complications associated with traditional balloon-occluded retrograde transvenous obliteration (BRTO).
Area of Science:
- Gastroenterology and Interventional Radiology
- Hepatology
- Vascular Interventions
Background:
- Gastric varices are a serious complication of liver cirrhosis, leading to significant bleeding and mortality.
- Transjugular intrahepatic portosystemic shunt (TIPS) and balloon-occluded retrograde transvenous obliteration (BRTO) are established treatments.
- Traditional BRTO faces challenges in China due to complication risks, limiting its acceptance.
Observation:
- Modified BRTO techniques, including coil-assisted (CARTO) and plug-assisted (PARTO) methods, are emerging as safer alternatives.
- These modified techniques aim to overcome the limitations and complications of conventional BRTO.
- This report details the first reported case of CARTO performed in China for gastric varices bleeding.
Findings:
- Coil-assisted retrograde transvenous obliteration (CARTO) was successfully employed to treat gastric varices bleeding.
- The procedure demonstrated efficacy in managing this severe complication of portal hypertension.
- The case highlights the potential of CARTO as a viable treatment option in the Chinese population.
Implications:
- CARTO presents a potentially safer and effective alternative to traditional BRTO for gastric varices in liver cirrhosis patients.
- This case report may encourage wider adoption and further investigation of CARTO in China.
- Further research is warranted to establish the long-term outcomes and comparative effectiveness of CARTO versus other interventions.
Abstract:
Gastric varices are a major complication of portal hypertension in patients with liver cirrhosis and are associated with more massive bleeding events and higher mortality rate. Transjugular intrahepatic portosystemic shunt (TIPS) and balloon-occluded retrograde transvenous obliteration (BRTO) have been well documented as effective therapies for portal hypertensive gastric variceal bleeding. In China, TIPS are well accepted but BRTO is not well recieved due to the increase risk of complications associated with traditional BRTO. However, modified-BRTO, known as coil-assisted and plug-assisted retrograde transvenous obliteration (CARTO and PARTO, respectively), is receiving increased attention due to devoid of BRTO's shortcomings. No CARTO case from China has been reported in literature thus far. Here, we present a Chinese case of CARTO to treat gastric varices bleeding.
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