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Related Concept Videos

Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

445
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
445
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

565
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
565
Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

410
Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
410
Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

245
Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
245
Irritable Bowel Syndrome I: Introduction01:17

Irritable Bowel Syndrome I: Introduction

543
Irritable Bowel Syndrome (IBS) is characterized by functional disturbances in the gastrointestinal system, presenting a cluster of symptoms without evident structural or biochemical abnormalities. It primarily affects the large intestine and may cause abdominal pain, bloating, excessive gas, diarrhea, constipation, or both.
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
543
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

451
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
451

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Related Experiment Video

Updated: Oct 12, 2025

Investigating Intestinal Inflammation in DSS-induced Model of IBD
08:43

Investigating Intestinal Inflammation in DSS-induced Model of IBD

Published on: February 1, 2012

67.8K

Silent Inflammatory Bowel Disease.

Matthew D Coates1,2, David G Binion3

  • 1Department of Medicine, Division of Gastroenterology & Hepatology, Penn State College of Medicine, Hershey, Pennsylvania, USA.

Crohn'S & Colitis 360
|November 22, 2021
PubMed
Summary
This summary is machine-generated.

Silent Inflammatory Bowel Disease (IBD) involves active inflammation with few symptoms, potentially leading to serious complications. Further research is crucial for better diagnosis and treatment of this under-recognized condition.

Keywords:
Crohn’s diseaseasymptomatic active diseasesilent inflammatory bowel diseaseulcerative colitisvisceral hypoalgesia

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Area of Science:

  • Gastroenterology
  • Clinical Medicine
  • Patient Outcomes

Background:

  • Inflammatory Bowel Disease (IBD) presents with significant symptoms impacting quality of life and healthcare costs.
  • Silent IBD, characterized by reduced symptom perception despite active inflammation, poses a risk for severe complications and costly interventions.
  • This under-recognized condition affects a substantial number of patients with Crohn's disease and ulcerative colitis.

Purpose of the Study:

  • To critically review existing studies on silent IBD.
  • To discuss the definition, epidemiology, causes, and diagnostic methods for silent IBD.
  • To identify knowledge gaps and explore potential novel diagnostic and therapeutic strategies.

Main Methods:

  • Literature review of studies investigating silent IBD.
  • Analysis of methods used to define silent IBD.
  • Examination of epidemiological data, potential etiologies, and current diagnostic tools.

Main Results:

  • Silent IBD is associated with active inflammation but diminished symptom reporting.
  • The exact causes and contributors to silent IBD remain largely unknown.
  • Current diagnostic methods for identifying at-risk patients are limited.

Conclusions:

  • Improved understanding of silent IBD is essential for developing effective diagnostic and treatment approaches.
  • Further research may lead to novel strategies for managing silent IBD and related gastrointestinal disorders.
  • Addressing silent IBD can potentially reduce severe complications and healthcare expenditures.