Related Experiment Video
Updated: Oct 12, 2025
12:17
An In Vitro Caseum Binding Assay that Predicts Drug Penetration in Tuberculosis Lesions
Published on: May 8, 2017
12.1K
Clots in tuberculosis
B H Ng1, Y L B Andrea2, N A Nuratiqah1
1Pusat Perubatan Universiti Kebangsaan Malaysia, Department of Internal Medicine, Respiratory Unit, Malaysia.
The Medical Journal of Malaysia
|November 22, 2021
Summary
Tuberculosis (TB) patients face risks of venous thromboembolism (VTE), often undetected. Early anticoagulant and anti-TB treatment are crucial for managing TB-associated thrombosis.
Area of Science:
- Internal Medicine
- Infectious Diseases
- Cardiology
Background:
- Tuberculosis (TB) is a prevalent infectious disease.
- Active TB infection can lead to venous and arterial thrombosis, which are frequently underdiagnosed.
- Thrombotic complications in TB patients require increased clinical attention.
Purpose of the Study:
- To highlight the association between tuberculosis and venous thromboembolism (VTE).
- To present cases of incidental TB-associated thrombosis.
- To emphasize the need for vigilance regarding VTE in TB patients.
Main Methods:
- Case report of two patients with incidental TB-associated thrombosis.
- Review of clinical presentation, diagnostic findings, and treatment outcomes.
- Analysis of the relationship between anti-tuberculous therapy (ATT) and VTE.
Main Results:
- Two patients presented with thrombosis in different venous systems, incidentally discovered alongside active TB.
- Both patients responded favorably to combined anticoagulant and anti-tuberculous therapy (ATT).
- The findings underscore the potential for silent VTE in active TB infections.
Conclusions:
- Patients with active tuberculosis are at increased risk for VTE.
- Close monitoring for VTE is essential during the course of ATT.
- A high index of suspicion for silent VTE is critical in managing TB patients.
More Related Videos
09:02An Experimental Model to Study Tuberculosis-Malaria Coinfection upon Natural Transmission of Mycobacterium tuberculosis and Plasmodium berghei
Published on: February 17, 2014
20.0K
10:10A 3D Human Lung Tissue Model for Functional Studies on Mycobacterium tuberculosis Infection
Published on: October 5, 2015
19.1K
Related Concept Videos
01:28Pulmonary Tuberculosis II
619
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
619
01:31Pulmonary Tuberculosis III
511
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
The first classification is based on the development of the disease, and it includes the following categories:
511
01:29Pulmonary Tuberculosis I
393
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
393
01:26Pulmonary Tuberculosis IV
227
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
227
01:28Pulmonary Tuberculosis V
264
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
264
01:30Venous Thrombosis I: Introduction
72
Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...
72