Related Experiment Video
Updated: Oct 12, 2025

Surgical Transplantation of Tumor Cells into the Spinal Cord of Mice
Published on: December 27, 2024
Spontaneous Regression of Multiple Pulmonary Metastasis of Sacral Chordoma: A Case Report
Kaito Takagi1, Akihito Nagano1, Masanori Tsugita1
1The Department of Orthopaedic Surgery, Gifu University School of Medicine, Gifu, Japan.
Case:
A 53-year-old man was referred to our institution for the treatment of sacral chordoma and underwent a wide resection. Multiple lung metastases were observed in both the lungs, a year after the surgery, and the diagnosis was confirmed by biopsy. The patient refused treatment, and the lesions continued to increase in size gradually. However, 3 years and 6 months after the surgery, computed tomography of both the lungs showed spontaneous regression of the lesions without any obvious causes. The metastatic lung lesions had disappeared at the final follow-up, 7 years and 5 months after the multiple pulmonary metastases were diagnosed.
Conclusion:
We report the first case of spontaneous regression of pathologically proven pulmonary metastases of a sacral chordoma.

