Related Experiment Video
Updated: Oct 12, 2025
12:00
Procedures for Identifying Infectious Prions After Passage Through the Digestive System of an Avian Species
Published on: November 6, 2013
11.3K
Experimental Oronasal Transmission of Chronic Wasting Disease Agent from White-Tailed Deer to Suffolk Sheep
Emerging Infectious Diseases
|November 22, 2021
Abstract:
Chronic wasting disease (CWD) is a fatal prion disease of cervids. We examined host range of CWD by oronasally inoculating Suffolk sheep with brain homogenate from a CWD-positive white-tailed deer. Sixty months after inoculation, 1/7 sheep had immunoreactivity against the misfolded form of prion protein in lymphoid tissue. Results were confirmed by mouse bioassay.
