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Related Experiment Videos

Surface interactions on hydrogel contact lenses: scanning electron microscopy (SEM).

D E Hart1

  • 1Contact Lens Research Foundation, Jericho, NY 11753.

Journal of the American Optometric Association
|December 1, 1987
PubMed
Summary

Hydrogel contact lenses worn continuously develop anterior surface coatings within two weeks. This coating, along with lens degradation, can cause adverse reactions and vision problems.

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Area of Science:

  • Ophthalmology
  • Materials Science
  • Biomaterials

Background:

  • Contact lens wear can lead to surface deposition and degradation.
  • Understanding these changes is crucial for preventing adverse events and maintaining visual acuity.

Purpose of the Study:

  • To investigate the interactions between tear film and hydrogel contact lens surfaces.
  • To characterize the deposited material and polymer surface changes during wear.
  • To correlate these changes with potential causes of discomfort and vision impairment.

Main Methods:

  • Scanning Electron Microscopy (SEM) was employed to visualize lens surface topography.
  • Hydrogel lenses were preserved using a quaternary ammonium complex for mucin preservation.
  • Lenses were obtained from patients experiencing continuous wear and conjunctivitis.

Main Results:

  • Complete anterior lens surface coating occurred within two weeks of continuous wear.
  • The posterior lens surface remained largely free of coating.
  • Observed degradation, deformation, and entrapment of moieties within the polymer matrix.
  • Conjunctivitis induced significant lens contamination, deformation, and deposition, though intact microbes were rare in the mucoprotein layer.

Conclusions:

  • Anterior surface deposition and polymer degradation are significant consequences of hydrogel contact lens wear.
  • These alterations likely contribute to adverse patient reactions, light scatter, and reduced vision.
  • Lens changes associated with conjunctivitis highlight the impact of ocular conditions on contact lens performance.

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