Reflectance confocal microscopy: Melanocytic and nonmelanocytic
Related Experiment Video
Updated: Oct 12, 2025

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition
Published on: August 18, 2022
Neda Shahriari1, Harold Rabinovitz2, Margaret Oliviero2
1Department of Dermatology, University of Connecticut School of Medicine, Farmington, Connecticut, USA.
Abstract:
Reflectance confocal microscopy (RCM) is a noninvasive imaging tool that has the potential to revolutionize dermatology. Extensive research in this area in conjunction with the recent assignment of reimbursement codes has made the clinical use of this technology a practical reality. Though there is awareness and use of this technology at large academic centers, a knowledge gap still remains in interpreting RCM images among the dermatology community. We review the key RCM features of melanocytic and nonmelanocytic lesions to provide guidance in distinguishing benign entities from malignant dermatologic neoplasms.
Related Concept Videos
Confocal Fluorescence Microscopy
Skin Cancer
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...

