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Related Concept Videos

Disorders of the Skeletal Muscle01:28

Disorders of the Skeletal Muscle

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The clinical conditions affecting the skeletal muscle tissue are broadly categorized as musculoskeletal and neuromuscular disorders.
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
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Disorders of the Nervous Tissue01:28

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Nervous tissue is a vital component of the human body's communication system, enabling us to perceive and respond to stimuli. However, like all other tissues, it is vulnerable to disorders and diseases that can significantly impact our neurological functioning.
Homeostatic Imbalances:
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Parkinson's disease arises from the...
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Ankle Joint01:10

Ankle Joint

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The ankle is formed by the talocrural joint (crural = leg). It consists of the articulations between the talus bone of the foot and the distal ends of the tibia and fibula of the leg. The superior aspect of the talus bone is square-shaped and has three areas of articulation. The top of the talus articulates with the inferior tibia. This is the portion of the ankle joint that carries the body weight between the leg and foot. The sides of the talus are firmly held in position by the articulations...
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Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation01:21

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

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Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
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Disorders of the Autonomic Nervous System01:18

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The autonomic nervous system (ANS) is an intricate network of nerves that controls functions such as the regulation of heart rate, digestion, and blood pressure regulation. When this system malfunctions, it can lead to various disorders that affect multiple bodily functions. One common feature of many autonomic disorders is the involvement of smooth blood vessels, which play a crucial role in regulating blood flow throughout the body.
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Muscles of the Leg that Move the Foot and Toes01:28

Muscles of the Leg that Move the Foot and Toes

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The human leg comprises an intricate system of muscles that facilitate the movement of feet and toes. Within this system, the muscles are categorized into the anterior, lateral, and posterior compartments, each with a unique set of muscles carrying out specific functions.
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Related Experiment Video

Updated: Oct 12, 2025

Evaluating the Function of the Foot Core System in the Elderly
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Neurologic Disorders Affecting the Foot and Ankle.

William R Yorns1

  • 1Department of Neurology, UCONN School of Medicine, Connecticut Children's Medical Center, 505 Farmington Avenue., 2nd Floor, Farmington, CT 06032, USA.

Clinics in Podiatric Medicine and Surgery
|November 23, 2021
PubMed
Summary

Neurologic conditions affecting the foot and leg can cause significant dysfunction and ambulation problems. Accurate diagnosis through physical examination and testing is crucial for effective treatment of these sensorimotor disorders.

Keywords:
AtaxiaCerebral palsyCharcot–Marie–Tooth diseaseImmune-mediated polyneuropathiesNerve entrapmentPeripheral neuropathy

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Area of Science:

  • Neurology
  • Orthopedics
  • Physical Therapy

Background:

  • Foot and leg dysfunction frequently stems from neurologic origins.
  • Sensorimotor disturbances in the lower extremities impair ambulation and necessitate medical attention.

Purpose of the Study:

  • To review the neurologic causes of foot and leg dysfunction.
  • To highlight the importance of clinical evaluation and diagnostic testing for accurate diagnosis.

Main Methods:

  • Literature review of neurologic disorders affecting the foot and leg.
  • Discussion of peripheral nerve, muscle, and central nervous system conditions.

Main Results:

  • Neurologic disorders are a common cause of foot and leg pain, weakness, and sensorimotor issues.
  • Effective management requires identifying the specific neurologic etiology.

Conclusions:

  • Understanding the neurologic basis of foot and leg dysfunction is key for appropriate diagnosis and treatment.
  • A comprehensive approach combining clinical assessment and diagnostic testing is essential for patient care.