Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Drug Therapy01:28

Drug Therapy

117
The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
117
Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

24
Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
24
Dosage Regimen: Individualization01:24

Dosage Regimen: Individualization

11
Individualization in dosing regimens is the customization of medication doses for individual patients. Its necessity arises from the goal of maximizing therapeutic benefits while minimizing risks. This approach is pivotal because human responses to drugs can vary widely; what is effective for one person may be inadequate or excessive for another. Interpatient (intersubject) variability refers to differences in drug responses between individuals, while intrapatient (intrasubject) variability...
11
Dosage Regimens: Designs and Approaches01:28

Dosage Regimens: Designs and Approaches

22
Designing a dosage regimen, which refers to the manner of drug administration, is a complex process involving the selection of drug dose, route, and frequency. This process is underpinned by pharmacokinetic parameters derived from tests and population averages. These parameters are then tailored to patient-specific variables such as diagnosis, demographics, and allergy status. Once therapy commences, therapeutic response monitoring is critical and achieved through clinical and physical...
22
Drug Dependence01:17

Drug Dependence

1.2K
Medications are typically administered to achieve therapeutic effects. Some drugs can modify an individual's mood and perception, frequently resulting in various enjoyable experiences. However, this can result in drug dependency, a condition marked by continuous drug use despite potential negative consequences. Drug dependency primarily falls into two categories: psychological and physical dependence. Psychological dependence occurs when the pleasurable feelings induced by the drug...
1.2K
Bioequivalence of Drugs: Drugs with Multiple Indications01:09

Bioequivalence of Drugs: Drugs with Multiple Indications

13
The concept of therapeutic equivalence (TE) in drugs with multiple indications is complex. A generic drug may be therapeutically equivalent to a brand-name product for one specific indication, but this doesn't necessarily mean it's equivalent for all other indications. Evidence of TE in one patient group and bioequivalence shown in healthy volunteers can support—but not confirm—TE for other indications. However, definitive proof requires individual clinical studies for each...
13

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Direct oral anticoagulants vs warfarin in Asian vs non-Asian patients with atrial fibrillation: a patient-level meta-analysis from COMBINE AF.

European heart journal·2026
Same author

Duration and dose of allopurinol needed to attain the serum urate target in gout.

Scandinavian journal of rheumatology·2026
Same author

Association Between Social Determinants of Health and Adherence to Antihypertensive Medications in US Patients With Uncontrolled, Treated Hypertension.

Circulation. Population health and outcomes·2026
Same author

Feasibility of Implementing a Clinical Integration Package to Support Self-Measured Blood Pressure Monitoring in Primary Care: A Qualitative Study.

Circulation. Population health and outcomes·2026
Same author

Delayed Access to Insulin During Pregnancy.

Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·2026
Same author

Characterizing Adherence to a Mobile Health App for Patient-Reported Outcomes in Rheumatoid Arthritis.

Rheumatology and therapy·2026

Related Experiment Video

Updated: Oct 12, 2025

Determining Pain Detection and Tolerance Thresholds Using an Integrated, Multi-Modal Pain Task Battery
09:38

Determining Pain Detection and Tolerance Thresholds Using an Integrated, Multi-Modal Pain Task Battery

Published on: April 14, 2016

12.9K

Exploring patient experiences coping with using multiple medications: a qualitative interview study.

Julie C Lauffenburger1,2, Nancy Haff3,2, Marie E McDonnell4

  • 1Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA jlauffenburger@bwh.harvard.edu.

BMJ Open
|November 23, 2021
PubMed
Summary

Poor adherence to cardiometabolic disease medications is common. Patients find medication-taking inconvenient and alter regimens due to medication properties and developed coping strategies.

Keywords:
cardiologydiabetes & endocrinologypublic healthqualitative researchtherapeutics

More Related Videos

Enactive Phenomenological Approach to the Trier Social Stress Test: A Mixed Methods Point of View
05:26

Enactive Phenomenological Approach to the Trier Social Stress Test: A Mixed Methods Point of View

Published on: January 7, 2019

6.9K
High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry
10:17

High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry

Published on: April 23, 2019

9.9K

Related Experiment Videos

Last Updated: Oct 12, 2025

Determining Pain Detection and Tolerance Thresholds Using an Integrated, Multi-Modal Pain Task Battery
09:38

Determining Pain Detection and Tolerance Thresholds Using an Integrated, Multi-Modal Pain Task Battery

Published on: April 14, 2016

12.9K
Enactive Phenomenological Approach to the Trier Social Stress Test: A Mixed Methods Point of View
05:26

Enactive Phenomenological Approach to the Trier Social Stress Test: A Mixed Methods Point of View

Published on: January 7, 2019

6.9K
High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry
10:17

High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry

Published on: April 23, 2019

9.9K

Area of Science:

  • Cardiology
  • Endocrinology
  • Pharmacology

Background:

  • Long-term adherence to evidence-based medications for cardiometabolic diseases is poor.
  • Interventions have limited success, potentially due to ignored patient experiences with medication-taking.
  • Exploring patient perspectives is crucial as medication use increases.

Purpose of the Study:

  • To explore patient perspectives on medication-taking.
  • To identify medication properties that act as barriers to adherence.
  • To understand coping strategies employed by patients for their medication regimens.

Main Methods:

  • Conducted individual, in-person, semistructured qualitative interviews.
  • Included 26 adults with diabetes, hypertension, or hyperlipidaemia non-adherent to ≥2 oral medications.
  • Analyzed interview data using developed codes to generate themes.

Main Results:

  • Medication-taking is often viewed as inconvenient and difficult to remember.
  • Patients deviate from prescribed regimens due to inconvenience, illness perceptions, and medication properties (e.g., size, appearance).
  • Patients develop coping strategies and suggest improvements like reduced costs, simpler regimens, and palatable medications.

Conclusions:

  • Patients with poor adherence perceive medication-taking as undesirable and alter regimens.
  • Medication properties and coping strategies significantly impact adherence.
  • Interventions should focus on reducing inconvenience and personalizing medication use.