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Updated: Oct 12, 2025

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Perceived Disease Activity in Rheumatoid Arthritis: When the Physician's Gender Matters.

Ilaria Duca1, Bruno Lucchino1, Frascesca Romana Spinelli1

  • 1Department of Clinical, Internal, Anesthetic and Cardiovascular Science-Rheumatology Unit, Sapienza University of Rome, Rome, Italy.

The Israel Medical Association Journal : IMAJ
|November 23, 2021
PubMed
Summary
This summary is machine-generated.

Physician gender influences rheumatoid arthritis (RA) disease activity assessment, with female physicians reporting higher subjective measures. Patients perceive higher disease activity than physicians, and female physicians show better agreement with patients.

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Area of Science:

  • Rheumatology
  • Clinical assessment
  • Gender studies

Background:

  • Rheumatoid arthritis (RA) often has a worse prognosis in females.
  • The impact of physician gender on RA activity assessment is not well understood.

Purpose of the Study:

  • To examine differences in RA disease activity assessment between male and female physicians.
  • To compare patient and physician perceptions of disease activity and global health (GH).

Main Methods:

  • 154 RA patients were evaluated by one female and one male rheumatologist.
  • Data collected included tender/swollen joint counts, GH, evaluator global assessment (EGA), and patient global assessment (PGA).
  • Disease activity scores (DAS28, CDAI, SDAI) were calculated; differences and agreement were statistically analyzed.

Main Results:

  • Global health, PGA, and DAS28 scores were higher when assessed by the female physician.
  • Male EGA was higher; male patients reported higher PGA with the female examiner.
  • Disease activity assessment was not dependent on physician gender, but physician-patient agreement was higher with the female physician.

Conclusions:

  • Subjective RA disease activity measures vary between male and female rheumatologists.
  • Patients generally report higher disease activity than physicians perceive.
  • Female physicians may foster a more empathetic environment, leading to better physician-patient agreement.