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Brain Imaging

Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans), magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...

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Related Experiment Video

Updated: Oct 12, 2025

A Multimodal Imaging- and Stimulation-based Method of Evaluating Connectivity-related Brain Excitability in Patients with Epilepsy

A Multimodal Imaging- and Stimulation-based Method of Evaluating Connectivity-related Brain Excitability in Patients with Epilepsy

Published on: November 13, 2016

Advanced neuroimaging techniques in epilepsy.

John S Duncan^1,2, Karin Trimmel^1,2,3

¹Department of Clinical and Experimental Epilepsy, UCL Queen Square Institute of Neurology, London.

Current Opinion in Neurology

|November 23, 2021

Summary

This summary is machine-generated.

Advanced epilepsy imaging techniques like high-field MRI and multimodal imaging improve seizure detection and surgical planning. These methods reveal widespread brain network abnormalities, aiding in predicting surgical outcomes and minimizing risks for epilepsy patients.

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Last Updated: Oct 12, 2025

A Multimodal Imaging- and Stimulation-based Method of Evaluating Connectivity-related Brain Excitability in Patients with Epilepsy

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Published on: November 13, 2016

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Area of Science:

Neuroimaging
Epileptology
Radiology

Background:

Epilepsy diagnosis and management rely heavily on identifying underlying brain abnormalities.
Advances in neuroimaging offer new insights into the structural and functional correlates of epilepsy.

Purpose of the Study:

To review recent significant advances in epilepsy imaging.
To highlight the diagnostic and prognostic value of novel imaging techniques.

Main Methods:

Review of structural MRI (7T), diffusion MRI, functional MRI (fMRI), and Positron Emission Tomography (PET).
Analysis of multi-site MRI data and connectivity studies.
Evaluation of 3D multimodal imaging for surgical precision.

Main Results:

Optimized 7T MRI enhances diagnostic yield, though artifacts persist.
MRI reveals distinct atrophy and white matter patterns in different epilepsy types, often near the seizure focus.
Connectivity MRI aids in understanding seizure spread and predicting surgical outcomes.
fMRI predicts postoperative deficits, and PET probes neurochemical pathways.

Conclusions:

Improved MRI detects more epilepsy-related abnormalities.
Advanced imaging, including diffusion, structural, and functional MRI, identifies widespread network associations in epilepsy.
These techniques assist in stratifying surgical outcomes and minimizing risks.
PET remains valuable for clinical studies and epilepsy pathophysiology research.