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Sensitive skin: Active ingredients on the spotlight.

Marta S Ferreira1,2, José M Sousa Lobo1,2, Isabel F Almeida1,2

  • 1Associate Laboratory i4HB-Institute for Health and Bioeconomy, Faculty of Pharmacy, University of Porto, Porto, Portugal.

International Journal of Cosmetic Science
|November 23, 2021
PubMed
Summary
This summary is machine-generated.

Niacinamide and Avena sativa are the top active ingredients in sensitive skin facial care products. While many ingredients target skin inflammation and barrier repair, robust clinical evidence for their efficacy in sensitive skin remains limited.

Keywords:
allergyclaim substantiationcosmeticsinflammationsensitive skinskin careskin physiologystructure

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Area of Science:

  • Dermatology and Cosmetic Science
  • Ingredient Analysis
  • Product Formulation

Background:

  • Sensitive skin is defined by heightened sensory perceptions to non-injurious stimuli.
  • Cosmetic formulations for sensitive skin aim to alleviate these symptoms.
  • The pharmacy and parapharmacy channels offer specialized products for sensitive skin concerns.

Purpose of the Study:

  • To identify and rank the most frequently used active ingredients in facial care products for sensitive skin.
  • To compile scientific evidence on the efficacy and mechanisms of action of these ingredients.
  • To inform healthcare professionals and formulators about ingredient trends and evidence gaps.

Main Methods:

  • Analysis of 88 facial care products labeled for sensitive, reactive, or intolerant skin.
  • Identification and ranking of active ingredients based on product composition.
  • Literature review of scientific evidence for ingredient mechanisms and efficacy.

Main Results:

  • Niacinamide, Avena sativa, allantoin, glycyrrhetinic acid, and Laminaria ochroleuca were the most common ingredients.
  • Over 50% of products contained ingredients targeting skin inflammation and barrier repair.
  • Clinical evidence supporting ingredient efficacy in sensitive skin populations is sparse and often lacks methodological rigor.

Conclusions:

  • Niacinamide is the leading active ingredient in sensitive skin cosmetics.
  • There is a need for higher quality clinical studies on active ingredients for sensitive skin.
  • Findings support dermatologists in advising patients and guide future cosmetic product development.