Skin in the game.

Area of Science:

• Ophthalmology
• Infectious Diseases
• Neurology

Background:

• Toxoplasma gondii is a common parasite that can cause opportunistic infections.
• Ocular toxoplasmosis can lead to significant visual impairment.

Observation:

• A 23-year-old male with a history of migraines and seizures presented with sudden, painless left eye vision loss.
• Examination revealed optic disc edema; brain and orbital MRI were unremarkable.
• The patient reported frequent, unprotected handling and consumption of raw deer meat, often with hand cuts.

Findings:

• Serum analysis revealed significantly elevated Toxoplasma gondii IgG and IgM antibodies, confirming acute infection.
• The clinical presentation and serological findings were consistent with ocular toxoplasmosis.

Implications:

• This case highlights the risk of acquiring toxoplasmosis through occupational or recreational exposure to infected animals, particularly undercooked meat.
• Early diagnosis of ocular toxoplasmosis is essential for timely treatment and visual preservation.
• Physicians should consider Toxoplasma gondii in the differential diagnosis of optic neuropathy, especially in at-risk individuals.