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Updated: Oct 12, 2025

An Allele-specific Gene Expression Assay to Test the Functional Basis of Genetic Associations
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One Hundred Years of Gene Balance: How Stoichiometric Issues Affect Gene Expression, Genome Evolution, and

James A Birchler1, Reiner A Veitia2,3,4

  • 1Division of Biological Sciences, University of Missouri, Columbia, Missouri, USA.

Cytogenetic and Genome Research
|November 23, 2021
PubMed

Keywords:
AneuploidyDosage compensationGene balance hypothesisHaploinsufficiencyInverse effectPolyploidyQuantitative trait lociSex chromosome evolutionWhole-genome duplication

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