Related Experiment Video
Updated: Oct 12, 2025
Translaminar Autonomous System Model for the Modulation of Intraocular and Intracranial Pressure in Human Donor Posterior Segments
Published on: April 24, 2020
[Postmortem intraocular pressure values in children (0-3 years old) depending on time elapsed from the moment of
D N Uslontsev1,2, Z Yu Sokolova3,4
1D.I. Mastbaum Bureau of Forensic Medicine, Ryazan, Russia.
Insights
Intraocular pressure in children aged 0-3 years provides reliable data. Postmortem intraocular pressure can help determine time of death in deceased children within 3 hours, with over 95% accuracy.
Area of Science:
- Forensic Medicine
- Ophthalmology
- Pediatrics
Background:
- Intraocular pressure (IOP) is a critical physiological parameter.
- Establishing normal IOP ranges in pediatric populations is essential for clinical and forensic applications.
- Accurate postmortem interval (PMI) estimation is crucial in forensic investigations.
Purpose of the Study:
- To analyze intravital intraocular pressure values in children aged 0 to 3 years.
- To evaluate the utility of postmortem intraocular pressure measurements for determining the postmortem interval in young children.
- To establish the predictive accuracy of IOP measurements in both living and deceased pediatric subjects.
Main Methods:
- Analysis of medical records for 1,643 children to determine intravital IOP.
- Calculation of average intravital IOP values for age groups 0-2 years and 2-3 years.
- 12,960 postmortem IOP measurements from 192 deceased children (0-3 years) within 1 to 12 hours postmortem.
Main Results:
- Intravital IOP averaged 14±2 mm Hg for ages 0-2 years and 15±3 mm Hg for ages 2-3 years, with >95% prediction accuracy.
- Postmortem IOP measurements demonstrated potential as an additional criterion for PMI estimation.
- A minimum postmortem interval of 3 hours could be predicted with >95% accuracy using postmortem IOP.
Conclusions:
- Intravital IOP values in children aged 0-3 years are well-defined and predictable.
- Postmortem intraocular pressure measurements offer a reliable method for estimating the postmortem interval in deceased children.
- IOP analysis, both intravital and postmortem, provides valuable data in pediatric forensic and clinical contexts.
Abstract:
This article presents data on the analysis of intravital and postmortem intraocular pressure values in children aged 0 to 3 years. Intravital intraocular pressure values were analyzed according to medical records in 1 643 children, and the average values were calculated. The intravital intraocular pressure values in children aged 0 to 2 years were found to be 14±2 mm Hg, and in children aged 2 to 3 years, 15±3 mm Hg, with an error-free prediction probability of more than 95 %. Postmortem intraocular pressure values were determined in 12 960 measurements in 192 deceased patients with a time elapsed from the moment of death ranging from 1 to 12 hours. It was demonstrated that postmortem intraocular pressure values in the examination of deceased children aged 0 to 3 years can be used as an additional criterion in determining the time of death as a postmortem interval with a probability of error-free prediction not less than 95 % with the minimum range not less than 3 hours.
