Related Experiment Video
Updated: Oct 12, 2025

Investigating Drivers of Antireward in Addiction Behavior with Anatomically Specific Single-Cell Gene Expression Methods
Published on: August 4, 2022
Dying with dignity: the challenges of end-of-life care in patients with substance use disorders
Prasun Datta1, Jeffrey S Kruk2, Kylie Jordan1
1Centre for Addiction Medicine, Nepean Hospital, Penrith, New South Wales, Australia.
Abstract:
Substance use disorder is a chronic disease carrying a high risk of morbidity and mortality. We report a case of a patient on long-term opioid agonist treatment who was diagnosed with metastatic cholangiocarcinoma and was referred to palliative care services almost contemporaneously with this diagnosis. In this report, we explore the challenges posed in offering holistic care during the end of life of a patient with a history of opioid dependence. A coordinated approach by addiction medicine and palliative care teams can allow patients from this complex cohort to ultimately die with dignity.
Related Concept Videos
Substance Use Disorders Affecting Sleep
Understanding the concepts of physical dependence,...
Ethical Issues
Ethical Concerns in Healthcare:
Ethical Dilemmas II
Nursing Ethical Principles II
Consider the following scenario, which illustrates how these principles are applied in the care of Mr. John, a fifty-year-old teacher diagnosed with metastatic liver cancer.
Initially, Mr. John's...
Drug Dosing: Geriatric Patients
Restorative Care

