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Updated: Oct 12, 2025
Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
Published on: May 26, 2023
Bacillary layer detachment on optical coherence tomography in exudative age-related macular degeneration
Ramesh Venkatesh1, Nikitha G Reddy1, Sameeksha Agrawal1
1Department of Retina-Vitreous, 80219Narayana Nethralaya, Bengaluru, India.
Purpose:
To report the bacillary layer detachment on optical coherence tomography in exudative age-related macular degeneration.
Methods:
Retrospective, observational cases.
Case Descriptions:
Two cases of exudative age-related macular degeneration, one diagnosed as polypoidal choroidal vasculopathy following exudative age-related macular degeneration and other as wet age-related macular degeneration with choroidal neovascular membrane showed separation of myoid and ellipsoid zones of photoreceptor layer on optical coherence tomography. This is termed as BALAD. Other associated features noted were the presence of subretinal hyperreflective material, submacular hemorrhage and subretinal fluid. Both cases were treated with monthly intravitreal injections of Inj. Ranibizumab (0.5 mg/0.05 ml). Following 3 intravitreal injections at monthly intervals, reattachment of the bacillary layer detachment were noted in case 1 while the bacillary layer detachment persisted in case 2.
Conclusion:
Multimodal imaging using optical coherence tomography in these cases revealed the separation of the bacillary layer following exudative age-related macular degeneration; a finding which is not routinely described in literature.
