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Updated: Oct 12, 2025

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In Vesiculo Synthesis of Peptide Membrane Precursors for Autonomous Vesicle Growth
Published on: June 28, 2019
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Facile formation of giant elastin-like polypeptide vesicles as synthetic cells
Bineet Sharma1, Yutao Ma2, Harrison L Hiraki3
1Department of Mechanical Engineering, University of Michigan, Ann Arbor, Michigan 48109, USA. allenliu@umich.edu.
Abstract:
We demonstrate the facile and robust generation of giant peptide vesicles by using an emulsion transfer method. These robust vesicles can sustain chemical and physical stresses. The peptide vesicles can host cell-free expression reactions by encapsulating essential ingredients. We show the incorporation of another cell-free expressed elastin-like polypeptide into the existing membrane of the peptide vesicles.

